PDBsum entry 3lx6

Transferase

PDB id: 3lx6

Contents

Protein chains

368 a.a. *

Waters ×29

* Residue conservation analysis

PDB id:

3lx6

Name:

Transferase

Title:

Crystal structure of putative DNA cytosine methylase from shigella flexneri 2a str. 2457t

Structure:

Cytosine-specific methyltransferase. Chain: a, b. Engineered: yes

Source:

Shigella flexneri 2a. Organism_taxid: 198215. Strain: 2457t. Gene: dcm, s2100, sf2005, sf2457t_1495. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.29Å R-factor: 0.245 R-free: 0.288

Authors:

U.A.Ramagopal,R.Toro,S.K.Burley,S.C.Almo,New York Sgx Research Center For Structural Genomics (Nysgxrc)

Key ref:

U.A.Ramagopal et al. Structure of probable cytosine-Specific methyltransferase(64-462)from shigella flexneri. To be published, .

Date:

24-Feb-10 Release date: 23-Mar-10

Protein chains

E3Y0J2  (E3Y0J2_SHIFL) -

Enzyme reactions

• Enzyme class: E.C.2.1.1.37 - Dna (cytosine-5-)-methyltransferase.
• Reaction: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl- 2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site