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PDBsum entry 3ldb

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protein ligands metals Protein-protein interface(s) links
Immune system PDB id
3ldb

 

 

 

 

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Contents
Protein chains
334 a.a. *
217 a.a. *
210 a.a. *
Ligands
GOL ×5
SO4 ×19
AKG
Metals
_HG ×2
_FE
* Residue conservation analysis
PDB id:
3ldb
Name: Immune system
Title: Structure of jmjd6 complexd with alpha-ketoglutarate and fab fragment.
Structure: Bifunctional arginine demethylase and lysyl-hydroxylase jmjd6. Chain: a. Synonym: histone arginine demethylase jmjd6, peptide-lysine 5- dioxygenase jmjd6, lysyl-hydroxylase jmjd6, jmjc domain-containing protein 6, jumonji domain-containing protein 6, phosphatidylserine receptor, protein ptdsr. Engineered: yes. Antibody fab fragment light chain.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: jmjd6, jmjd6 (1-403), kiaa0585, ptdsr. Expressed in: escherichia coli. Expression_system_taxid: 562. Cricetulus migratorius. Organism_taxid: 10032. Cell: hybridoma.
Resolution:
2.70Å     R-factor:   0.250     R-free:   0.285
Authors: X.Hong,J.Zang,J.White,J.W.Kappler,C.Wang,G.Zhang
Key ref: X.Hong et al. (2010). Interaction of JMJD6 with single-stranded RNA. Proc Natl Acad Sci U S A, 107, 14568-14572. PubMed id: 20679243
Date:
12-Jan-10     Release date:   04-Aug-10    
PROCHECK
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 Headers
 References

Protein chain
Q6NYC1  (JMJD6_HUMAN) -  Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 from Homo sapiens
Seq:
Struc:
403 a.a.
334 a.a.
Protein chain
No UniProt id for this chain
Struc: 217 a.a.
Protein chain
No UniProt id for this chain
Struc: 210 a.a.
Key:    Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: Chain A: E.C.1.14.11.-  - ?????
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
Proc Natl Acad Sci U S A 107:14568-14572 (2010)
PubMed id: 20679243  
 
 
Interaction of JMJD6 with single-stranded RNA.
X.Hong, J.Zang, J.White, C.Wang, C.H.Pan, R.Zhao, R.C.Murphy, S.Dai, P.Henson, J.W.Kappler, J.Hagman, G.Zhang.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23235912 Y.Yang, and M.T.Bedford (2013).
Protein arginine methyltransferases and cancer.
  Nat Rev Cancer, 13, 37-50.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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