PDBsum entry 3knm Go to PDB code:  Pore analysis for: 3knm calculated with MOLE 2.0 PDB id 3knm Pores calculated on whole structure Pores calculated excluding ligands View options MOLEonline 2.0 manipulation and visualization with HETATM: without HETATM:   30 pores, coloured by radius 30 pores, coloured by radius 30 pores, coloured as in list below Pores are connected internal spaces going through the structure. Only pores longer than 25 Å are shown. Pores Free R Length HPathy HPhob Polar Rel Mut Residue..type Ligands Radius 1 1.55 1.55 85.9 -1.35 -0.51 14.9 79 7 3 2 1 2 2 1  A 2469 A C 2474 A C 2475 A A 2476 A C 2527 A A 2530 A G 2532 A A 2654 A U 2656 A A 2657 A A 2665 A 2 1.60 2.10 103.7 -0.62 -0.41 14.8 78 8 5 0 9 2 0 0  C 2295 A U 2296 A C 2297 A C 2313 A C 2314 A G 2315 A C 2316 A G 2338 A G 2339 A G 2340 A G 2341 A C 30 B C 31 B C 32 B G 33 B U 41 B C 42 B C 43 B A 45 B A 46 B A 53 B A 58 B A 59 B 3 2.60 2.60 105.6 -1.08 -0.70 12.6 70 6 2 0 1 2 0 0  A 866 A U 871 A A 872 A G 873 A G 874 A G 882 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A C 903 A C 904 A U 905 A G 906 A C 2316 A C 2317 A G 2318 A G 2319 A MG 3072 A C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B C 68 B G 69 B MG 635 Z 4 1.82 2.97 114.0 -1.80 -0.73 22.6 86 7 6 2 1 0 0 0  C 865 A A 866 A U 871 A A 872 A G 873 A G 874 A G 882 A G 883 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A C 903 A C 904 A U 905 A G 906 A C 1040 A C 1116 A A 2469 A A 2476 A MG 3072 A G 103 B 5 2.68 2.68 121.8 -1.17 -0.77 14.3 75 7 2 0 1 0 0 0  G 1002 A G 1003 A C 1004 A U 1012 A C 1013 A U 1014 A G 1015 A G 1016 A G 1031 A A 1032 A C 1116 A G 1117 A C 1118 A C 1119 A G 1120 A C 1121 A G 1122 A U 1142 A A 1142 A i:A A 1143 A G 1144 A C 1145 A C 1146 A C 1147 A A 1148 A G 1149 A A 2469 A A 2476 A MG 3020 A C 84 B G 85 B G 86 B G 87 B G 89 B A 90 B C 92 B G 93 B C 94 B 6 1.85 1.85 151.1 -1.36 -0.70 15.7 80 7 3 2 2 1 0 0  G 864 A C 865 A A 866 A U 871 A A 872 A G 873 A G 874 A G 882 A G 883 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A C 903 A C 904 A U 905 A G 906 A G 1002 A G 1003 A C 1004 A U 1012 A C 1013 A U 1014 A G 1015 A G 1016 A C 1119 A G 1120 A A 1142 A i:A U 1142 A A 1143 A G 1144 A C 1145 A C 1146 A C 1147 A A 1148 A G 1149 A MG 3020 A MG 3072 A U 77 B A 78 B C 84 B G 85 B G 93 B C 94 B G 101 B A 102 B G 103 B 7 1.78 2.94 156.5 -1.54 -0.65 19.3 78 11 7 2 2 3 0 0  A 866 A C 903 A C 904 A U 905 A C 1040 A C 1116 A C 2316 A C 2317 A G 2318 A G 2319 A A 2469 A A 2476 A C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B C 68 B G 69 B G 103 B 8 1.68 2.17 165.8 -0.24 -0.40 9.9 82 6 4 1 10 0 1 0  A 866 A C 867 A U 868 A G 869 A U 871 A A 872 A G 873 A G 874 A G 882 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A A 901 A C 902 A C 903 A U 905 A G 906 A A 2287 A A 2288 A A 2310 A G 2321 A A 2322 A G 2323 A G 2325 A C 2326 A A 2327 A A 2328 A G 2340 A G 2341 A MG 3072 A U 41 B MG 635 Z 9 1.97 1.97 173.6 -0.44 -0.61 7.9 68 6 0 0 2 0 0 0  C 313 A A 314 A G 317 A C 318 A G 323 A G 333 A G 530 A G 533 A U 534 A C 535 A G 552 A G 553 A U 554 A U 555 A G 556 A U 557 A G 558 A G 559 A C 560 A G 561 A G 978 A G 979 A A 980 A A 981 A G 1003 A C 1004 A C 1008 A U 1012 A C 1013 A U 1014 A G 1015 A G 1016 A C 1135 A G 1136 A U 1142 A A 1142 A i:A A 1143 A G 1144 A C 1145 A C 1146 A C 1147 A G 1149 A G 1206 A C 1207 A C 1208 A G 1209 A A 1210 A U 1211 A G 1212 A A 1213 A A 1214 A G 1215 A C 1217 A C 1218 A G 1219 A A 1220 A C 1221 A i:A C 1221 A G 1223 A G 1227 A G 1228 A G 1229 A C 1230 A G 1231 A C 2021 A G 2037 A G 2038 A MG 3020 A MG 3098 A MG 3177 A 10 1.60 1.60 209.0 -0.79 -0.77 8.6 86 4 1 1 1 0 0 0  A 824 A C 825 A U 826 A U 827 A U 828 A A 829 A G 859 A A 866 A U 871 A A 872 A G 873 A G 874 A G 882 A G 883 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A C 903 A C 904 A U 905 A G 906 A C 914 A C 915 A G 1839 A G 1840 A U 1841 A G 1842 A C 1893 A C 1894 A U 2076 A G 2246 A C 2254 A G 2255 A U 2257 A G 2259 A C 2260 A C 2263 A C 2264 A U 2265 A A 2266 A G 2270 A G 2271 A U 2272 A A 2273 A A 2274 A G 2319 A A 2320 A G 2330 A G 2331 A U 2332 A C 2424 A A 2425 A A 2426 A C 2427 A A 2430 A U 2431 A A 2434 A A 2435 A G 2436 A U 2437 A G 2595 A U 2596 A G 2597 A MG 3000 A MG 3071 A MG 3072 A MG 3192 A MG 3214 A G 69 B C 70 B 11 1.57 1.57 221.9 -1.05 -0.74 11.7 76 8 2 1 1 2 0 0  A 824 A C 825 A U 826 A U 827 A U 828 A A 829 A G 859 A C 914 A C 915 A G 1839 A G 1840 A U 1841 A G 1842 A C 1893 A C 1894 A U 2076 A G 2246 A C 2254 A G 2255 A U 2257 A G 2259 A C 2260 A C 2263 A C 2264 A U 2265 A A 2266 A G 2270 A G 2271 A U 2272 A A 2273 A A 2274 A C 2316 A C 2317 A G 2318 A G 2319 A A 2320 A G 2330 A G 2331 A U 2332 A A 2333 A C 2424 A A 2425 A A 2426 A C 2427 A A 2430 A U 2431 A A 2434 A A 2435 A G 2436 A U 2437 A G 2595 A U 2596 A G 2597 A MG 3000 A MG 3052 A MG 3071 A MG 3192 A MG 3214 A G 16 B C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B 12 2.28 2.29 219.7 -0.99 -0.74 11.0 71 9 3 0 1 2 1 0  U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A G 950 A C 967 A G 968 A G 979 A C 985 A C 986 A G 1002 A G 1003 A C 1004 A U 1012 A C 1013 A U 1014 A G 1015 A G 1016 A G 1025 A U 1026 A U 1142 A A 1142 A i:A A 1143 A G 1144 A C 1145 A C 1146 A C 1147 A G 1149 A C 2316 A C 2317 A G 2318 A G 2319 A A 2320 A G 2331 A U 2332 A A 2333 A MG 3020 A MG 3213 A G 16 B C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B G 81 B G 82 B G 83 B C 84 B G 85 B G 86 B G 87 B G 89 B 13 1.59 2.28 261.5 -0.41 -0.55 8.8 84 6 4 2 10 0 1 0  A 824 A C 825 A U 826 A U 827 A U 828 A A 829 A G 859 A C 867 A U 868 A G 869 A U 913 A C 914 A G 1839 A G 1840 A U 1841 A G 1842 A C 1893 A C 1894 A U 2076 A G 2246 A C 2254 A G 2255 A U 2257 A G 2259 A C 2260 A C 2263 A C 2264 A U 2265 A A 2266 A G 2270 A G 2271 A U 2272 A A 2273 A A 2274 A A 2287 A A 2288 A G 2321 A A 2322 A G 2323 A G 2325 A C 2326 A A 2327 A A 2328 A G 2329 A G 2330 A G 2331 A G 2340 A G 2341 A C 2424 A A 2425 A A 2426 A C 2427 A A 2430 A U 2431 A A 2434 A A 2435 A G 2436 A U 2437 A G 2595 A U 2596 A G 2597 A MG 3000 A MG 3071 A MG 3192 A MG 3214 A U 41 B 14 2.66 2.66 258.3 -0.46 -0.76 4.2 70 1 0 0 0 1 0 0  C 949 A G 950 A A 959 A C 961 A G 979 A C 985 A G 1002 A G 1003 A C 1004 A U 1012 A C 1013 A U 1014 A G 1015 A G 1016 A G 1025 A U 1026 A U 1142 A A 1142 A i:A A 1143 A G 1144 A C 1145 A C 1146 A C 1147 A G 1149 A G 1839 A G 1840 A U 1841 A G 1842 A C 1893 A C 1894 A C 2063 A U 2076 A G 2252 A G 2253 A C 2254 A G 2255 A A 2435 A G 2436 A U 2437 A A 2439 A A 2451 A U 2457 A G 2458 A A 2459 A U 2460 A C 2461 A U 2462 A C 2463 A C 2464 A C 2465 A C 2480 A G 2481 A G 2482 A G 2485 A G 2486 A G 2487 A A 2488 A U 2492 A U 2493 A U 2506 A C 2507 A C 2520 A U 2537 A U 2554 A U 2555 A C 2556 A G 2557 A G 2567 A C 2568 A G 2569 A C 2573 A U 2585 A G 2595 A U 2596 A G 2597 A A 2600 A C 2601 A A 2602 A MG 2998 A MG 3020 A MG 3119 A MG 3120 A MG 3226 A G 86 B G 87 B C 88 B G 89 B 15 2.37 2.37 245.6 -0.68 -0.79 6.9 83 4 1 0 0 0 0 0  G 312 A C 313 A G 317 A C 318 A G 323 A G 325 A G 326 A A 332 A G 333 A C 334 A G 836 A C 837 A U 839 A C 840 A A 841 A G 842 A G 843 A C 844 A G 845 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A A 866 A U 871 A A 872 A G 873 A G 874 A G 882 A G 883 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A C 903 A C 904 A U 905 A G 906 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A G 932 A G 934 A C 935 A C 936 A U 937 A U 1167 A G 1168 A G 1193 A A 1194 A G 1195 A C 1196 A G 1197 A U 1198 A U 1199 A C 1200 A C 1201 A C 1202 A G 1203 A A 1204 A G 1206 A C 1207 A G 1209 A G 1239 A U 1240 A A 1241 A G 1244 A G 1245 A G 2319 A A 2320 A G 2331 A U 2332 A U 2357 A MG 3054 A MG 3072 A MG 3182 A G 69 B C 70 B 16 2.28 2.28 258.4 -0.95 -0.75 10.2 74 8 2 0 0 2 0 0  G 312 A C 313 A G 317 A C 318 A G 323 A G 325 A G 326 A A 332 A G 333 A C 334 A G 836 A C 837 A U 839 A C 840 A A 841 A G 842 A G 843 A C 844 A G 845 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A G 932 A G 934 A C 935 A C 936 A U 937 A U 1167 A G 1168 A G 1193 A A 1194 A G 1195 A C 1196 A G 1197 A U 1198 A U 1199 A C 1200 A C 1201 A C 1202 A G 1203 A A 1204 A G 1206 A C 1207 A G 1209 A G 1239 A U 1240 A A 1241 A G 1244 A G 1245 A C 2316 A C 2317 A G 2318 A G 2319 A A 2320 A G 2331 A U 2332 A A 2333 A U 2357 A MG 3054 A MG 3182 A G 16 B C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B 17 1.76 1.75 278.0 -1.01 -0.57 14.8 84 16 6 2 11 0 2 0  G 1022 A U 1023 A A 1027 A A 1028 A A 1029 A G 1031 A A 1032 A C 1116 A G 1117 A C 1118 A C 1119 A G 1120 A C 1121 A G 1122 A C 1123 A C 1124 A G 1125 A A 1126 A A 1127 A U 1133 A A 2469 A A 2476 A A 2541 A A 2542 A G 2543 A U 2636 A U 2637 A G 2638 A A 2639 A G 2641 A G 2642 A G 2644 A G 2645 A U 2739 A C 2767 A C 2768 A C 2769 A G 2770 A C 2771 A C 2772 A C 2773 A C 2774 A A 2775 A G 2819 A A 2820 A A 2821 A C 2827 A C 2828 A U 2836 A G 2837 A G 2844 A C 2874 A C 2875 A G 2876 A MG 3097 A MG 3158 A MG 3191 A 18 1.67 2.27 272.9 -0.48 -0.57 9.1 81 9 5 1 10 0 2 0  U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 867 A U 868 A G 869 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A G 950 A C 967 A G 968 A G 979 A C 985 A C 986 A G 1002 A G 1003 A C 1004 A U 1012 A C 1013 A U 1014 A G 1015 A G 1016 A G 1025 A U 1026 A U 1142 A A 1142 A i:A A 1143 A G 1144 A C 1145 A C 1146 A C 1147 A G 1149 A A 2287 A A 2288 A G 2321 A A 2322 A G 2323 A C 2324 A G 2325 A C 2326 A A 2327 A A 2328 A G 2329 A G 2330 A G 2331 A U 2332 A G 2340 A G 2341 A MG 3020 A MG 3213 A U 41 B G 81 B G 82 B G 83 B C 84 B G 85 B G 86 B G 87 B G 89 B 19 1.79 1.78 273.6 -1.10 -0.55 15.9 85 14 8 3 12 0 3 0  U 1012 A C 1013 A U 1014 A G 1015 A G 1016 A G 1017 A U 1142 A A 1142 A i:A U 2636 A U 2637 A G 2638 A A 2639 A G 2737 A A 2738 A U 2739 A A 2758 A G 2759 A C 2760 A C 2769 A G 2770 A C 2771 A C 2772 A C 2773 A C 2774 A A 2775 A G 2819 A A 2820 A A 2821 A C 2827 A C 2828 A U 2836 A G 2837 A G 2844 A C 2874 A C 2875 A G 2876 A MG 3020 A MG 3191 A 20 1.71 2.12 275.9 -0.73 -0.62 11.8 82 12 7 1 9 0 2 0  U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 867 A U 868 A G 869 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A G 950 A C 967 A G 968 A G 979 A C 985 A C 986 A G 1024 A G 1025 A U 1026 A A 1028 A A 1029 A G 1031 A A 1032 A C 1116 A G 1117 A C 1118 A C 1119 A G 1120 A C 1121 A G 1122 A C 1145 A C 1146 A A 2287 A A 2288 A G 2321 A A 2322 A G 2323 A C 2324 A G 2325 A C 2326 A A 2327 A A 2328 A G 2329 A G 2330 A G 2331 A U 2332 A G 2340 A G 2341 A A 2469 A A 2476 A U 41 B G 81 B G 82 B G 83 B C 84 B G 85 B G 86 B G 87 B C 88 B G 89 B 21 2.43 2.41 299.3 -0.61 -0.74 7.4 82 7 3 2 3 0 1 0  C 34 A G 35 A C 39 A C 40 A G 54 A U 67 A G 68 A G 89 A U 90 A A 92 A G 93 A A 181 A A 182 A C 183 A C 238 A U 239 A C 433 A U 434 A C 435 A C 436 A G 437 A G 452 A G 458 A U 475 A G 476 A A 479 A A 480 A A 590 A C 591 A G 592 A G 593 A U 594 A C 595 A G 596 A U 597 A A 608 A A 609 A G 656 A U 657 A C 658 A C 659 A G 660 A C 661 A A 835 A G 836 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A A 866 A U 871 A A 872 A G 873 A G 874 A G 882 A G 883 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A C 903 A C 904 A U 905 A G 906 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A C 935 A C 936 A U 937 A G 938 A G 2319 A A 2320 A G 2331 A U 2332 A U 2357 A MG 3072 A MG 3182 A G 69 B C 70 B 22 1.69 2.09 311.6 -0.45 -0.59 8.4 84 8 4 1 9 0 1 0  G 312 A C 313 A G 317 A C 318 A G 323 A G 325 A G 326 A A 332 A G 333 A C 334 A G 836 A C 837 A U 839 A C 840 A A 841 A G 842 A G 843 A C 844 A G 845 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 867 A U 868 A G 869 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A G 932 A G 934 A C 935 A C 936 A U 937 A U 1167 A G 1168 A G 1193 A A 1194 A G 1195 A C 1196 A G 1197 A U 1198 A U 1199 A C 1200 A C 1201 A C 1202 A G 1203 A A 1204 A G 1206 A C 1207 A G 1209 A G 1239 A U 1240 A A 1241 A G 1244 A G 1245 A A 2287 A A 2288 A G 2321 A A 2322 A G 2323 A C 2324 A G 2325 A C 2326 A A 2327 A A 2328 A G 2329 A G 2330 A G 2331 A U 2332 A G 2340 A G 2341 A U 2357 A MG 3054 A MG 3182 A U 41 B 23 2.59 2.62 312.1 -0.84 -0.72 10.0 77 11 4 2 3 2 1 0  C 34 A G 35 A C 39 A C 40 A G 54 A U 67 A G 68 A G 89 A U 90 A A 92 A G 93 A A 181 A A 182 A C 183 A C 238 A U 239 A C 433 A U 434 A C 435 A C 436 A G 437 A G 452 A G 458 A U 475 A G 476 A A 479 A A 480 A A 590 A C 591 A G 592 A G 593 A U 594 A C 595 A G 596 A U 597 A A 608 A A 609 A G 656 A U 657 A C 658 A C 659 A G 660 A C 661 A A 835 A G 836 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A C 935 A C 936 A U 937 A G 938 A C 2316 A C 2317 A G 2318 A G 2319 A A 2320 A G 2331 A U 2332 A A 2333 A U 2357 A MG 3182 A G 16 B C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B 24 2.95 2.95 314.8 -0.73 -0.75 8.9 80 10 4 2 3 0 1 0  C 34 A G 35 A C 39 A C 40 A G 54 A U 67 A G 68 A G 89 A U 90 A A 92 A G 93 A A 181 A A 182 A C 183 A C 238 A U 239 A C 433 A U 434 A C 435 A C 436 A G 437 A G 452 A G 458 A U 475 A G 476 A A 479 A A 480 A A 590 A C 591 A G 592 A G 593 A U 594 A C 595 A G 596 A U 597 A A 608 A A 609 A G 656 A U 657 A C 658 A C 659 A G 660 A C 661 A A 821 A U 822 A A 835 A G 836 A C 837 A U 922 A C 935 A C 936 A U 937 A G 938 A G 947 A G 948 A C 949 A G 950 A C 951 A A 960 A C 961 A U 963 A C 964 A C 965 A G 966 A C 967 A G 968 A U 969 A G 979 A C 985 A G 1024 A G 1025 A U 1026 A A 1028 A A 1029 A G 1031 A A 1032 A C 1116 A G 1117 A C 1118 A C 1119 A G 1120 A C 1121 A G 1122 A C 1145 A C 1146 A G 2270 A U 2357 A A 2469 A A 2476 A MG 3073 A MG 3142 A MG 3173 A G 86 B G 87 B C 88 B G 89 B 25 1.49 1.49 333.0 -0.51 -0.59 8.3 81 9 5 1 10 2 2 0  U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 867 A U 868 A G 869 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A C 949 A G 950 A A 959 A C 961 A C 967 A G 968 A C 985 A C 986 A U 1026 A A 2287 A A 2288 A G 2321 A A 2322 A G 2323 A C 2324 A G 2325 A C 2326 A A 2327 A A 2328 A G 2329 A G 2330 A G 2331 A U 2332 A G 2340 A G 2341 A U 2457 A G 2458 A A 2459 A U 2460 A C 2461 A C 2463 A C 2464 A C 2465 A C 2480 A G 2481 A G 2482 A G 2485 A G 2486 A G 2487 A A 2488 A C 2520 A C 2521 A U 2522 A G 2523 A G 2524 A G 2525 A G 2526 A U 2528 A A 2530 A G 2532 A A 2533 A A 2534 A G 2535 A G 2536 A U 2537 A C 2538 A A 2654 A U 2656 A A 2657 A A 2665 A C 2666 A MG 2998 A MG 3119 A MG 3208 A MG 3231 A U 41 B G 81 B G 82 B G 83 B C 84 B G 85 B G 86 B C 88 B G 89 B 26 1.76 1.76 357.6 -0.67 -0.74 7.5 79 8 3 2 2 2 1 0  C 40 A C 184 A U 185 A G 186 A G 187 A G 205 A U 206 A G 219 A U 235 A C 236 A C 237 A C 238 A U 239 A G 254 A A 255 A U 373 A A 374 A C 375 A C 376 A C 377 A G 382 A U 383 A G 391 A C 392 A C 393 A A 394 A U 395 A G 396 A U 405 A G 406 A G 407 A G 408 A C 413 A C 414 A A 415 A C 416 A A 423 A G 424 A G 425 A C 433 A A 590 A C 591 A G 592 A G 593 A U 594 A C 595 A G 596 A U 597 A A 608 A A 609 A G 656 A U 657 A C 658 A C 659 A G 660 A C 661 A A 835 A G 836 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A C 935 A C 936 A U 937 A G 938 A G 1865 A C 1866 A A 1876 A A 1877 A C 1879 A C 1880 A C 2316 A C 2317 A G 2318 A G 2319 A A 2320 A G 2331 A U 2332 A A 2333 A U 2357 A G 2409 A MG 3084 A MG 3182 A G 16 B C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B 27 1.64 1.64 355.6 -0.80 -0.73 9.4 77 10 4 1 2 2 1 0  C 39 A C 40 A A 119 A G 122 A G 123 A G 131 A G 132 A A 149 A C 150 A G 178 A G 179 A G 180 A A 181 A A 182 A C 183 A C 184 A A 207 A C 208 A C 209 A A 211 A G 212 A C 238 A U 239 A C 433 A A 590 A C 591 A G 592 A G 593 A U 594 A C 595 A G 596 A U 597 A A 608 A A 609 A G 656 A U 657 A C 658 A C 659 A G 660 A C 661 A G 668 A G 799 A A 835 A G 836 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A C 935 A C 936 A U 937 A G 938 A C 1350 A G 1358 A A 1359 A G 1368 A G 1374 A C 1375 A C 1407 A C 1408 A G 1416 A C 1417 A G 1418 A A 1419 A U 1420 A U 1497 A C 1574 A C 1575 A U 1576 A C 1577 A U 1578 A A 1579 A C 1589 A C 2316 A C 2317 A G 2318 A G 2319 A A 2320 A G 2331 A U 2332 A A 2333 A U 2357 A MG 3080 A MG 3182 A G 16 B C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B 28 1.59 2.26 362.6 -0.39 -0.61 7.7 84 9 6 3 12 0 2 0  C 39 A C 40 A A 53 A G 54 A U 67 A G 68 A C 69 A G 75 A C 76 A C 77 A A 78 A G 79 A G 100 A G 102 A A 103 A U 104 A C 105 A C 106 A C 107 A U 108 A G 109 A G 110 A A 181 A A 182 A C 183 A C 238 A U 239 A C 433 A U 434 A C 435 A C 436 A G 437 A G 452 A G 458 A A 590 A C 591 A G 592 A G 593 A U 594 A C 595 A G 596 A U 597 A A 608 A A 609 A G 656 A U 657 A C 658 A C 659 A G 660 A C 661 A A 835 A G 836 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 867 A U 868 A G 869 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A C 935 A C 936 A U 937 A G 938 A A 2287 A A 2288 A G 2321 A A 2322 A G 2323 A G 2325 A C 2326 A A 2327 A A 2328 A G 2329 A G 2330 A G 2331 A U 2332 A G 2340 A G 2341 A U 2357 A MG 3182 A U 41 B C 42 B 29 2.13 2.27 365.5 -0.59 -0.74 7.4 82 7 3 1 3 0 1 0  C 39 A C 40 A A 119 A G 122 A G 123 A G 131 A G 132 A G 139 A i:A A 141 A A 149 A C 150 A G 178 A G 179 A G 180 A A 181 A A 182 A C 183 A C 184 A A 207 A C 208 A C 209 A A 211 A G 212 A C 238 A U 239 A C 433 A A 590 A C 591 A G 592 A G 593 A U 594 A C 595 A G 596 A U 597 A A 608 A A 609 A G 656 A U 657 A C 658 A C 659 A G 660 A C 661 A G 668 A G 799 A A 835 A G 836 A G 848 A A 849 A U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A A 866 A U 871 A A 872 A G 873 A G 874 A G 882 A G 883 A U 895 A A 896 A C 897 A C 898 A A 899 A A 900 A C 903 A C 904 A U 905 A G 906 A C 914 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A U 922 A C 923 A C 935 A C 936 A U 937 A G 938 A G 1343 A C 1350 A G 1358 A A 1359 A G 1368 A G 1374 A C 1375 A C 1404 A U 1405 A U 1406 A C 1407 A C 1408 A C 1409 A A 1419 A U 1420 A C 1588 A C 1589 A U 1590 A G 1591 A C 1592 A G 1593 A G 1594 A G 1595 A A 1596 A A 1597 A G 2319 A A 2320 A G 2331 A U 2332 A U 2357 A MG 3072 A MG 3182 A MG 3198 A G 69 B C 70 B 30 1.95 1.95 404.3 -0.94 -0.62 12.6 82 18 7 2 11 2 3 0  U 851 A G 852 A G 853 A G 854 A G 855 A C 856 A C 857 A U 858 A G 859 A C 915 A G 916 A A 917 A A 918 A G 919 A G 920 A G 921 A C 949 A G 950 A C 961 A C 967 A G 968 A C 985 A C 986 A G 1022 A U 1023 A U 1026 A A 1127 A A 1128 A U 1133 A G 2027 A U 2028 A G 2029 A C 2316 A C 2317 A G 2318 A G 2319 A A 2320 A G 2331 A U 2332 A A 2333 A U 2457 A G 2489 A A 2541 A A 2542 A G 2543 A U 2636 A U 2637 A G 2638 A A 2639 A G 2641 A G 2642 A G 2644 A G 2645 A U 2739 A C 2767 A C 2768 A C 2769 A G 2770 A C 2771 A C 2772 A C 2773 A C 2774 A A 2775 A G 2819 A A 2820 A A 2821 A C 2827 A C 2828 A U 2836 A G 2837 A G 2844 A C 2874 A C 2875 A G 2876 A MG 3097 A MG 3158 A MG 3191 A G 16 B C 17 B G 18 B C 30 B C 31 B C 32 B G 33 B A 45 B A 46 B A 53 B A 58 B A 59 B C 60 B G 81 B G 82 B G 83 B C 84 B G 85 B G 86 B G 89 B Residue-type_colouring Positive Negative Neutral Aliphatic Aromatic Pro & Gly Cysteine H,K,R D,E S,T,N,Q A,V,L,I,M F,Y,W P,G C Acknowledgement Pores were calculated by MOLE 2.0 program version 2.5.13.11.08 and visualized using Pymol 0.97rc.