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UniProt functional annotation for Q05909 | ||
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| UniProt code: Q05909. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Possesses tyrosine phosphatase activity. {ECO:0000250}. |
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| Catalytic activity: | |
Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA- COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858, ChEBI:CHEBI:82620; EC=3.1.3.48; Evidence={ECO:0000255|PROSITE- ProRule:PRU10044}; |
| Subunit: | |
Monomer; active form. Homodimer; inactive form (By similarity). Interacts with CNTN3, CNTN4, CNTN5 and CNTN6. {ECO:0000250, ECO:0000269|PubMed:20133774}. |
| Subcellular location: | |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissue specificity: | |
Detected in brain, lung, kidney, heart, liver, skeletal muscle, spleen and testes. It is developmentally regulated in the brain. |
| Similarity: | |
Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.