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UniProt functional annotation for A1CII2 | ||
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| UniProt code: A1CII2. |
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| Organism: | |
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Fumigati. |
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| Catalytic activity: | |
Reaction=5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2; Xref=Rhea:RHEA:10792, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:77657, ChEBI:CHEBI:137981; EC=4.1.1.21; Evidence={ECO:0000256|ARBA:ARBA00001244, ECO:0000256|PIRNR:PIRNR001340}; |
| Pathway: | |
Purine metabolism; IMP biosynthesis via de novo pathway; 5- amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5- phospho-D-ribosyl)imidazole (carboxylase route): step 1/1. {ECO:0000256|ARBA:ARBA00004747, ECO:0000256|PIRNR:PIRNR001340}. |
| Similarity: | |
In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. {ECO:0000256|ARBA:ARBA00006114, ECO:0000256|PIRNR:PIRNR001340}. |
Annotations taken from UniProtKB at the EBI.