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UniProt functional annotation for O67680 | ||
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| UniProt code: O67680. |
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| Organism: | |
Aquifex aeolicus (strain VF5). |
| Taxonomy: | |
Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex. |
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| Function: | |
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. {ECO:0000255|HAMAP-Rule:MF_00607}. |
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| Catalytic activity: | |
Reaction=adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L- methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)- dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:19609, Rhea:RHEA-COMP:10232, Rhea:RHEA-COMP:10233, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74411, ChEBI:CHEBI:74493; EC=2.1.1.182; Evidence={ECO:0000255|HAMAP-Rule:MF_00607}; |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00607}. |
| Similarity: | |
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. {ECO:0000255|HAMAP-Rule:MF_00607}. |
Annotations taken from UniProtKB at the EBI.