|
|
||
|
|
|
|
|
UniProt functional annotation for P31025 | ||
|
|
|
|
|
|
||
| UniProt code: P31025. |
|
||
| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
|
||
|
||
| Function: | |
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. |
|
||
| Subunit: | |
Predominantly monomer (PubMed:17869594). May form homodimer (PubMed:17869594). Interacts with LMBR1L; this interaction mediates the endocytosis of LCN1 (PubMed:11287427, PubMed:12591932). {ECO:0000269|PubMed:11287427, ECO:0000269|PubMed:12591932, ECO:0000269|PubMed:17869594}. |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate. |
| Similarity: | |
Belongs to the calycin superfamily. Lipocalin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.