UniProt functional annotation for P0A6A8

UniProt code: P0A6A8.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
Pathway: Lipid metabolism; fatty acid biosynthesis. {ECO:0000255|HAMAP- Rule:MF_01217}.
Subunit: Interacts with MukB. {ECO:0000269|PubMed:20921377}.
Subcellular location: Cytoplasm.
Ptm: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
Similarity: Belongs to the acyl carrier protein (ACP) family. {ECO:0000255|HAMAP-Rule:MF_01217}.

Annotations taken from UniProtKB at the EBI.