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UniProt functional annotation for Q9F663 | ||
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| UniProt code: Q9F663. |
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| Organism: | |
Klebsiella pneumoniae. |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella. |
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| Function: | |
Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency. |
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| Catalytic activity: | |
Reaction=a beta-lactam + H2O = a substituted beta-amino acid; Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627, ChEBI:CHEBI:140347; EC=3.5.2.6; |
| Activity regulation: | |
Not inhibited by EDTA, inhibited by clavulanic acid and tazobactam. {ECO:0000269|PubMed:11257029}. |
| Miscellaneous: | |
Initially two different KPC beta-lactamases were identified from two different Klebsiella (KPC-1 and KPC-2); they were later shown to be identical. |
| Similarity: | |
Belongs to the class-A beta-lactamase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.