UniProt functional annotation for P05820

UniProt code: P05820.

Organism: Escherichia coli.
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
 
Function: This is a calcium-requiring inhibitor for murein biosynthesis; it causes lysis of sensitive cells accompanied by murein degradation. The target site is possibly the cytoplasmic membrane.
 
Miscellaneous: This colicin requires TonB for its uptake.

Annotations taken from UniProtKB at the EBI.