UniProt functional annotation for Q81ZZ3

UniProt code: Q81ZZ3.

Organism: Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298).
Taxonomy: Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales; Nitrosomonadaceae; Nitrosomonas.
 
Catalytic activity: Reaction=Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.; EC=3.4.16.4; Evidence={ECO:0000256|ARBA:ARBA00000871};
Catalytic activity: Reaction=[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D- Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc- (1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa- cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma- D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+); Xref=Rhea:RHEA:23708, Rhea:RHEA-COMP:9602, Rhea:RHEA-COMP:9603, ChEBI:CHEBI:15378, ChEBI:CHEBI:58405, ChEBI:CHEBI:60033, ChEBI:CHEBI:78435; EC=2.4.1.129; Evidence={ECO:0000256|ARBA:ARBA00023988};
Pathway: Cell wall biogenesis; peptidoglycan biosynthesis. {ECO:0000256|ARBA:ARBA00004752}.
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004249}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004249}. Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Similarity: In the C-terminal section; belongs to the transpeptidase family. {ECO:0000256|ARBA:ARBA00007090}.
Similarity: In the N-terminal section; belongs to the glycosyltransferase 51 family. {ECO:0000256|ARBA:ARBA00007739}.

Annotations taken from UniProtKB at the EBI.