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UniProt functional annotation for P04386 | ||
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| UniProt code: P04386. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
This protein is a positive regulator for the gene expression of the galactose-induced genes such as GAL1, GAL2, GAL7, GAL10, and MEL1 which code for the enzymes used to convert galactose to glucose. It recognizes a 17 base pair sequence in (5'-CGGRNNRCYNYNCNCCG-3') the upstream activating sequence (UAS-G) of these genes. |
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| Subunit: | |
Binds DNA as a homodimer. Interacts directly with the mediator subunits GAL11/MED15 and SRB4/MED17. {ECO:0000269|PubMed:11478912, ECO:0000269|PubMed:9660972}. |
| Subcellular location: | |
Nucleus. |
| Domain: | |
the 9aaTAD motif (residues 862 to 870) is a transactivation domain present in a large number of yeast and animal transcription factors. {ECO:0000269|PubMed:17467953}. |
| Ptm: | |
Association between GAL11 and GAL4 may serve to expedite phosphorylation of GAL4. |
| Miscellaneous: | |
Present with 166 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
Annotations taken from UniProtKB at the EBI.