UniProt functional annotation for P02866

UniProt code: P02866.

Organism: Canavalia ensiformis (Jack bean) (Dolichos ensiformis).
Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade; NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Canavalia.
 
Function: D-mannose specific lectin.
 
Subunit: Homotetramer. {ECO:0000269|PubMed:2792084}.
Ptm: The mature chain consists of residues 164-281 followed by 30-148. To form a mature chain the precursor undergoes further post- translational modification after removal of the signal sequence; cleavage after Asn at positions 148, 163, and 281 is followed by transposition and ligation (By formation of a new peptide bond) of residues 164-281 and 30-148.
Miscellaneous: Binds one manganese (or another transition metal) ion and one calcium ion. The metal ions are essential for the saccharide- binding and cell-agglutinating activities.
Similarity: Belongs to the leguminous lectin family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.