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UniProt functional annotation for P10970 | ||
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| UniProt code: P10970. |
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| Organism: | |
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui). |
| Taxonomy: | |
Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales; Haloarculaceae; Haloarcula. |
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| Function: | |
This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. {ECO:0000255|HAMAP-Rule:MF_01331}. |
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| Function: | |
Contacts all 6 domains of the 23S rRNA, helping stabilize their relative orientation. An extended beta-hairpin in the C-terminus forms part of the polypeptide exit tunnel, in which it helps forms a bend with protein L4, while most of the rest of the protein is located at the polypeptide exit tunnel on the outside of the subunit. |
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| Subunit: | |
Part of the 50S ribosomal subunit. Contacts the macrolide antibiotic tylosin in the polypeptide exit tunnel. {ECO:0000255|HAMAP- Rule:MF_01331, ECO:0000269|PubMed:12150912, ECO:0000269|PubMed:12860128}. |
| Similarity: | |
Belongs to the universal ribosomal protein uL22 family. {ECO:0000255|HAMAP-Rule:MF_01331}. |
Annotations taken from UniProtKB at the EBI.