 |
PDBsum entry 3cme
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Tunnel analysis for: 3cme calculated with  MOLE 2.0
|
PDB id
|
|
|
|
3cme
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Tunnels calculated on whole structure |
|
Tunnels calculated excluding ligands
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
18 tunnels,
coloured by tunnel radius |
|
19 tunnels,
coloured by
tunnel radius
|
19 tunnels,
coloured as in
list below
|
|
|
|
|
|
Tunnels are interior spaces connected with the protein surrounding. Only channels longer than 15 Å are shown. |
|
|
|
|
|
|
|
Free R
|
|
|
|
|
|
|
Length
|
|
|
|
|
|
|
HPathy
|
|
|
|
|
|
|
HPhob
|
|
|
|
|
|
|
Polar
|
|
|
|
|
|
|
Rel Mut
|
|
|
|
|
|
|
Residue..type
|
|
|
|
|
|
|
Ligands
|
|
|
|
|
|
|
 |
Radius |
 |
1 |
 |
1.15 |
1.36 |
117.2 |
-0.91 |
-0.68 |
11.9 |
86 |
|
4 |
3 |
2 |
2 |
0 |
1 |
0 |
|
C 764 0 G 765 0 A 766 0 U 768 0 C 769 0 C 770 0 G
771 0 G 772 0 A 773 0 U 866 0 A 867 0 G 868 0 G
869 0 G 887 0 U 888 0 C 889 0 G 892 0 C 893 0 A
895 0 C 896 0 A 897 0 U 1359 0 C 1360 0 G 1460 0
U 1461 0 C 1474 0 G 1475 0 A 1476 0 C 1477 0 U
1478 0 C 1862 0 G 1863 0 G 1868 0 A 1869 0 U 1871
0 C 1872 0 A 2101 0 C 2248 0 A 2479 0 G 2480 0 MG
8038 0 SR 8930 A SR 8977 A
|
 |
|
2 |
 |
1.14 |
1.41 |
120.5 |
-0.44 |
-0.61 |
7.7 |
77 |
4 |
1 |
1 |
3 |
2 |
1 |
0 |
A 114 0 U 115 0 G 116 0 A 117 0 G 118 0 A 119 0 A
131 0 A 132 0 C 764 0 G 765 0 A 766 0 U 768 0 C
769 0 C 770 0 G 771 0 G 772 0 A 773 0 C 774 0 A
867 0 G 868 0 G 869 0 G 887 0 U 888 0 C 889 0 G
892 0 C 893 0 A 895 0 C 896 0 A 897 0 U 1359 0 C
1360 0 C 1462 0 U 1463 0 C 1474 0 G 1475 0 G 1481
0 A 2101 0 A 2479 0 G 2480 0 SR 8957 0
|
|
3 |
 |
1.15 |
1.36 |
130.2 |
-0.93 |
-0.70 |
10.1 |
83 |
3 |
3 |
4 |
3 |
0 |
1 |
0 |
C 197 0 A 198 0 A 199 0 C 200 0 A 212 0 U 214 0 A
215 0 U 651 0 G 652 0 C 685 0 A 686 0 G 689 0 G
690 0 G 691 0 G 742 0 A 756 0 A 761 0 C 762 0 C
763 0 C 764 0 G 765 0 A 766 0 A 895 0 C 896 0 A
897 0 A 926 0 U 927 0 G 1037 0 G 1038 0 G 1039 0
A 1040 0 U 1041 0 U 1359 0 C 1360 0 A 2101 0 A
2479 0 G 2480 0 SR 8914 0
|
|
4 |
 |
1.12 |
1.61 |
150.7 |
-0.46 |
-0.68 |
6.5 |
85 |
1 |
1 |
1 |
3 |
0 |
1 |
0 |
C 764 0 G 765 0 A 766 0 A 767 0 U 768 0 C 769 0 U
832 0 G 833 0 G 834 0 U 835 0 U 837 0 C 839 0 U
845 0 A 846 0 U 883 0 C 884 0 U 888 0 G 892 0 C
893 0 A 895 0 C 896 0 A 897 0 U 1359 0 C 1360 0 G
1751 0 C 1753 0 A 1822 0 G 1823 0 C 1824 0 U 1825
0 C 1826 0 G 1837 0 U 1838 0 G 2000 0 G 2001 0 U
2016 0 U 2017 0 A 2018 0 A 2019 0 C 2020 0 C 2021
0 A 2022 0 G 2023 0 A 2024 0 C 2026 0 G 2099 0 A
2101 0 A 2103 0 U 2478 0 A 2479 0 G 2480 0 G 2617
0 G 2642 0 G 2643 0 C 2644 0 G 2646 0 SR 8937 0
SR 8998 0
|
|
5 |
 |
1.09 |
1.57 |
155.8 |
-0.48 |
-0.74 |
5.9 |
86 |
1 |
2 |
1 |
3 |
0 |
1 |
0 |
G 568 0 A 569 0 C 583 0 U 624 0 U 625 0 U 626 0 A
632 0 C 633 0 G 634 0 C 764 0 G 765 0 G 901 0 C
1044 0 G 1045 0 G 1046 0 U 1047 0 G 1059 0 C 1060
0 C 1061 0 G 1077 0 A 1078 0 C 1080 0 A 1082 0 C
1083 0 U 1095 0 G 1100 0 U 1101 0 U 1122 0 A 1123
0 A 1124 0 U 1125 0 C 1126 0 C 1127 0 U 1128 0 G
1239 0 A 1248 0 U 1249 0 C 1250 0 C 1253 0 C 1254
0 A 1255 0 C 1256 0 C 1257 0 A 1358 0 U 1359 0 C
1360 0 G 2072 0 A 2101 0 G 2481 0 G 2482 0 A 2483
0 C 2533 0 U 2535 0 G 2537 0 MG 8002 0 MG 8037 0
NA 8542 0 G 88 9
|
|
6 |
 |
1.07 |
1.53 |
163.0 |
-0.78 |
-0.68 |
7.8 |
85 |
3 |
2 |
3 |
2 |
0 |
2 |
0 |
U 651 0 G 739 0 G 740 0 C 741 0 G 742 0 A 756 0 A
761 0 C 762 0 C 763 0 C 764 0 G 765 0 A 766 0 A
895 0 C 896 0 A 897 0 A 926 0 U 927 0 G 1037 0 G
1038 0 G 1039 0 A 1040 0 U 1041 0 U 1359 0 C 1360
0 A 2101 0 U 2322 0 G 2323 0 G 2324 0 U 2325 0 A
2370 0 G 2371 0 A 2372 0 U 2373 0 G 2374 0 A 2375
0 C 2376 0 U 2384 0 G 2385 0 U 2386 0 U 2387 0 G
2397 0 A 2398 0 G 2399 0 G 2400 0 A 2401 0 A 2402
0 C 2403 0 G 2418 0 U 2419 0 G 2421 0 U 2422 0 A
2479 0 G 2480 0 NA 8511 0 SR 8914 0 SR 8935 0
|
|
7 |
 |
1.13 |
1.63 |
162.2 |
-0.79 |
-0.68 |
8.7 |
83 |
3 |
2 |
2 |
2 |
0 |
2 |
0 |
U 651 0 G 739 0 G 740 0 C 741 0 G 742 0 A 756 0 A
761 0 C 762 0 C 763 0 C 764 0 G 765 0 A 766 0 A
895 0 C 896 0 A 897 0 A 926 0 U 927 0 G 1037 0 G
1038 0 G 1039 0 A 1040 0 U 1041 0 U 1359 0 C 1360
0 A 2101 0 A 2356 0 G 2357 0 U 2358 0 G 2359 0 C
2360 0 A 2361 0 A 2362 0 G 2363 0 A 2364 0 U 2384
0 G 2385 0 U 2386 0 U 2387 0 G 2397 0 A 2398 0 G
2399 0 G 2400 0 A 2401 0 U 2419 0 G 2420 0 G 2421
0 U 2422 0 C 2423 0 U 2424 0 G 2426 0 C 2427 0 A
2479 0 G 2480 0 NA 8511 0 SR 8914 0
|
|
8 |
 |
1.09 |
1.55 |
163.1 |
-0.45 |
-0.69 |
6.2 |
85 |
1 |
1 |
1 |
3 |
0 |
1 |
0 |
C 764 0 G 765 0 A 766 0 A 767 0 U 768 0 C 769 0 U
825 0 G 828 0 G 830 0 U 831 0 C 839 0 U 845 0 A
846 0 C 847 0 C 848 0 C 849 0 U 850 0 U 883 0 C
884 0 U 888 0 G 892 0 C 893 0 A 895 0 C 896 0 A
897 0 U 1359 0 C 1360 0 G 1378 0 A 1379 0 U 1405
0 A 1406 0 A 1407 0 G 1546 0 A 1547 0 A 1550 0 G
1636 0 A 1637 0 U 1638 0 U 1639 0 G 1703 0 G 1704
0 G 1706 0 G 1707 0 A 1710 0 A 1711 0 A 1712 0 G
1713 0 C 1714 0 A 1796 0 A 1797 0 C 1798 0 G 1799
0 G 1837 0 U 1838 0 G 2099 0 A 2101 0 A 2103 0 U
2478 0 A 2479 0 G 2480 0 C 2644 0 G 2646 0 NA
8531 0 NA 8569 0 SR 8937 0
|
|
9 |
 |
1.11 |
1.56 |
164.9 |
-0.80 |
-0.70 |
8.7 |
88 |
6 |
4 |
5 |
3 |
1 |
1 |
0 |
A 551 0 A 552 0 G 554 0 U 555 0 C 556 0 C 557 0 U
595 0 C 596 0 A 597 0 C 598 0 A 603 0 G 607 0 A
608 0 U 609 0 G 622 0 G 634 0 A 635 0 C 638 0 A
639 0 G 640 0 C 764 0 G 765 0 G 901 0 G 902 0 C
1320 0 A 1321 0 G 1323 0 G 1324 0 G 1325 0 C 1326
0 G 1327 0 G 1331 0 C 1332 0 U 1333 0 A 1355 0 A
1356 0 A 1357 0 A 1358 0 U 1359 0 C 1360 0 A 2101
0 G 2537 0
|
|
10 |
 |
1.08 |
1.57 |
171.3 |
-0.75 |
-0.67 |
8.8 |
82 |
4 |
2 |
3 |
3 |
1 |
1 |
0 |
C 18 0 U 19 0 G 20 0 G 21 0 U 22 0 G 23 0 G 24 0
G 467 0 U 468 0 A 476 0 A 477 0 U 510 0 G 512 0 A
513 0 G 514 0 C 515 0 G 518 0 A 519 0 U 548 0 A
549 0 C 550 0 A 551 0 A 552 0 G 553 0 A 603 0 G
604 0 C 605 0 C 764 0 G 765 0 A 766 0 U 768 0 C
769 0 A 844 0 U 883 0 U 888 0 C 889 0 G 892 0 C
893 0 A 895 0 C 896 0 A 897 0 A 1321 0 G 1322 0 G
1323 0 U 1336 0 G 1337 0 U 1338 0 U 1359 0 C 1360
0 G 1363 0 G 1364 0 A 1689 0 A 2101 0 A 2479 0 G
2480 0 MG 8068 0
|
|
11 |
 |
1.11 |
1.60 |
172.9 |
-1.00 |
-0.49 |
14.9 |
81 |
10 |
4 |
5 |
7 |
2 |
1 |
0 |
C 31 0 A 86 0 C 87 0 U 335 0 G 336 0 A 462 0 A
466 0 G 467 0 U 468 0 A 476 0 G 479 0 C 480 0 C
483 0 A 484 0 G 506 0 G 514 0 C 764 0 G 765 0 A
766 0 U 768 0 C 769 0 A 844 0 U 883 0 U 888 0 C
889 0 G 892 0 C 893 0 A 895 0 C 896 0 A 897 0 U
1359 0 C 1360 0 A 1427 0 A 1689 0 A 2101 0 A 2479
0 G 2480 0
|
|
12 |
|
1.07 |
1.55 |
173.3 |
-0.61 |
-0.70 |
8.8 |
85 |
3 |
3 |
1 |
4 |
0 |
1 |
0 |
C 764 0 G 765 0 A 766 0 A 767 0 U 768 0 C 769 0 U
825 0 G 828 0 A 829 0 G 830 0 U 831 0 C 839 0 U
845 0 A 846 0 C 847 0 C 848 0 C 849 0 U 850 0 U
883 0 C 884 0 U 888 0 G 892 0 C 893 0 A 895 0 C
896 0 A 897 0 U 1359 0 C 1360 0 A 1407 0 U 1408 0
G 1409 0 G 1410 0 A 1411 0 G 1498 0 U 1499 0 U
1505 0 G 1628 0 G 1629 0 C 1680 0 G 1681 0 A 1682
0 G 1695 0 U 1696 0 G 1697 0 U 1698 0 C 1699 0 G
1719 0 G 1837 0 U 1838 0 G 2099 0 A 2101 0 A 2103
0 U 2478 0 A 2479 0 G 2480 0 C 2644 0 G 2646 0 NA
8569 0 SR 8937 0 SR 8941 0 SR 8996 0
|
|
13 |
|
1.13 |
1.60 |
176.4 |
-1.00 |
-0.63 |
11.8 |
83 |
8 |
2 |
4 |
4 |
1 |
1 |
0 |
C 31 0 G 41 0 C 42 0 U 43 0 A 49 0 C 62 0 U 63 0
G 64 0 C 65 0 C 85 0 A 86 0 C 101 0 A 102 0 C 103
0 A 104 0 A 354 0 C 355 0 C 443 0 C 444 0 C 461 0
A 462 0 A 466 0 G 467 0 U 468 0 A 476 0 G 479 0 C
480 0 G 514 0 C 764 0 G 765 0 A 766 0 U 768 0 C
769 0 A 844 0 U 883 0 U 888 0 C 889 0 G 892 0 C
893 0 A 895 0 C 896 0 A 897 0 U 1359 0 C 1360 0 A
1427 0 A 1689 0 A 2101 0 A 2479 0 G 2480 0
|
|
14 |
|
1.08 |
1.56 |
174.9 |
-0.68 |
-0.75 |
6.8 |
85 |
3 |
3 |
4 |
2 |
0 |
1 |
0 |
U 624 0 U 625 0 U 626 0 A 632 0 C 633 0 G 634 0 C
764 0 G 765 0 G 901 0 C 1044 0 G 1045 0 G 1046 0
U 1047 0 G 1048 0 C 1049 0 A 1058 0 G 1059 0 C
1060 0 C 1061 0 U 1062 0 U 1120 0 C 1126 0 C 1127
0 U 1128 0 C 1129 0 U 1130 0 G 1131 0 A 1231 0 A
1232 0 A 1236 0 U 1237 0 C 1238 0 A 1358 0 U 1359
0 C 1360 0 G 2068 0 A 2101 0 G 2481 0 G 2482 0 A
2483 0 U 2492 0 C 2493 0 G 2524 0 G 2525 0 C 2533
0 U 2535 0 G 2537 0 C 2551 0 C 2552 0 A 2577 0 G
2578 0 G 2674 0 A 2675 0 C 2676 0 A 2677 0 A 2678
0 G 2679 0 C 2802 0 C 2803 0 C 2804 0 A 2805 0 C
2806 0 U 2808 0 MG 8002 0 MG 8018 0 NA 8542 0 SR
8954 0 C 91 9 G 92 9 A 93 9
|
|
15 |
|
1.10 |
1.60 |
186.6 |
-0.50 |
-0.69 |
6.5 |
92 |
1 |
4 |
6 |
6 |
0 |
1 |
0 |
U 624 0 U 625 0 U 626 0 A 632 0 C 633 0 G 634 0 C
764 0 G 765 0 G 901 0 G 956 0 C 1044 0 G 1045 0 G
1046 0 U 1047 0 G 1048 0 C 1049 0 G 1050 0 C 1051
0 G 1052 0 G 1055 0 G 1059 0 C 1060 0 C 1061 0 U
1062 0 A 1133 0 G 1135 0 U 1136 0 G 1137 0 C 1140
0 U 1141 0 C 1142 0 A 1215 0 G 1216 0 G 1217 0 U
1220 0 G 1221 0 A 1222 0 G 1223 0 G 1224 0 A 1358
0 U 1359 0 C 1360 0 A 2101 0 G 2481 0 G 2482 0 A
2483 0 C 2533 0 U 2535 0 G 2537 0 A 2783 0 A 2784
0 C 2785 0 G 2786 0 C 2787 0 MG 8002 0 NA 8542 0
A 80 9 C 81 9 G 92 9 G 94 9 C 95 9 C 96 9 NA 8544
9 SR 8907 H
|
|
16 |
|
1.09 |
1.53 |
189.0 |
-1.42 |
-0.67 |
18.6 |
82 |
8 |
10 |
5 |
5 |
1 |
1 |
0 |
A 466 0 G 467 0 U 468 0 A 476 0 A 495 0 G 496 0 A
498 0 G 499 0 G 514 0 C 764 0 G 765 0 A 766 0 U
768 0 C 769 0 A 844 0 U 883 0 U 888 0 C 889 0 G
892 0 C 893 0 A 895 0 C 896 0 A 897 0 U 1359 0 C
1360 0 A 1390 0 G 1391 0 A 1392 0 A 1393 0 A 1427
0 A 1434 0 A 1689 0 G 1727 0 A 2101 0 A 2479 0 G
2480 0 C 2833 0 U 2904 0 A 2905 0 A 2906 0 C 2907
0 SR 8991 0
|
|
17 |
|
1.17 |
1.36 |
197.2 |
-0.68 |
-0.69 |
8.2 |
82 |
6 |
2 |
1 |
2 |
0 |
1 |
0 |
A 191 0 A 192 0 G 203 0 A 204 0 U 205 0 G 206 0 U
207 0 C 208 0 G 209 0 U 210 0 U 211 0 A 212 0 G
213 0 A 226 0 A 227 0 C 228 0 G 229 0 C 230 0 A
232 0 U 233 0 A 234 0 C 235 0 G 237 0 C 238 0 C
240 0 C 271 0 A 272 0 A 378 0 G 379 0 U 409 0 A
410 0 G 428 0 A 429 0 A 430 0 U 645 0 G 646 0 U
647 0 G 648 0 U 649 0 C 650 0 A 665 0 A 666 0 A
750 0 U 751 0 U 753 0 G 754 0 G 755 0 A 756 0 C
757 0 A 761 0 C 762 0 C 763 0 C 764 0 G 765 0 A
766 0 A 895 0 C 896 0 A 897 0 U 1359 0 C 1360 0 A
2101 0 A 2479 0 G 2480 0 SR 8914 0 SR 8966 0 SR
8984 0
|
|
18 |
|
1.08 |
1.49 |
196.3 |
-1.04 |
-0.62 |
12.2 |
82 |
9 |
4 |
4 |
4 |
2 |
1 |
0 |
C 29 0 C 31 0 C 87 0 A 319 0 G 320 0 A 321 0 G
322 0 C 330 0 G 332 0 G 333 0 G 334 0 U 335 0 A
337 0 C 338 0 A 339 0 A 340 0 C 341 0 A 462 0 A
466 0 G 467 0 U 468 0 A 476 0 G 479 0 C 480 0 U
481 0 G 482 0 C 483 0 A 484 0 G 514 0 C 764 0 G
765 0 A 766 0 U 768 0 C 769 0 A 844 0 U 883 0 U
888 0 C 889 0 G 892 0 C 893 0 A 895 0 C 896 0 A
897 0 C 1342 0 U 1359 0 C 1360 0 A 1427 0 A 1689
0 A 2101 0 A 2479 0 G 2480 0
|
 |
19 |
|
1.13 |
2.28 |
22.4 |
2.02 |
0.69 |
6.4 |
77 |
1 |
1 |
0 |
7 |
2 |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
 |
Residue-type_colouring |
 |
|
|
|
Positive
|
Negative
|
Neutral
|
Aliphatic
|
Aromatic
|
Pro & Gly
|
Cysteine
|
|
H,K,R
|
D,E
|
S,T,N,Q
|
A,V,L,I,M
|
F,Y,W
|
P,G
|
C
|
|
|
|
MOLE 2.0 program