PDBsum entry 3cj8

Transferase

PDB id: 3cj8

Contents

Protein chains

219 a.a. *

Ligands

ACT

FMT ×7

PEG

Metals

_MG

_CL ×6

Waters ×515

* Residue conservation analysis

PDB id:

3cj8

Name:

Transferase

Title:

Crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n- succinyltransferase from enterococcus faecalis v583

Structure:

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n- acetyltransferase. Chain: a, b, c. Synonym: tetrahydrodipicolinate n-acetyltransferase, thp acetyltransferase, tetrahydropicolinate acetylase. Engineered: yes

Source:

Enterococcus faecalis. Organism_taxid: 1351. Strain: v583. Atcc: 700802. Gene: dapd, daph, ef_1133. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.

Resolution:

1.95Å R-factor: 0.204 R-free: 0.248

Authors:

K.Tan,L.Bigelow,S.Clancy,A.Joachimiak,Midwest Center For Structural Genomics (Mcsg)

Key ref:

K.Tan et al. The crystal structure of 2,3,4,5-Tetrahydropyridine-2-Carboxylate n-Succinyltransferase from enterococcus faecalis V583.. To be published, .

Date:

12-Mar-08 Release date: 25-Mar-08

Protein chains

Q836H8  (DAPH_ENTFA) -  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase from Enterococcus faecalis (strain ATCC 700802 / V583)

Seq: 233 a.a.

Struc: 219 a.a.

Enzyme reactions

• Enzyme class: E.C.2.3.1.89 - tetrahydrodipicolinate N-acetyltransferase.
• Reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = L-2-acetamido-6- oxoheptanedioate + CoA

Molecule diagrams generated from .mol files obtained from the KEGG ftp site