PDBsum entry 3cc4 Go to PDB code:  Pore analysis for: 3cc4 calculated with MOLE 2.0 PDB id 3cc4 Pores calculated on whole structure Pores calculated excluding ligands View options MOLEonline 2.0 manipulation and visualization with HETATM: without HETATM:   30 pores, coloured by radius 30 pores, coloured by radius 30 pores, coloured as in list below Pores are connected internal spaces going through the structure. Only pores longer than 25 Å are shown. Pores Free R Length HPathy HPhob Polar Rel Mut Residue..type Ligands Radius 1 1.79 1.85 124.8 -0.80 -0.74 7.3 80 2 2 1 1 1 3 0  A 1729 0 G 1730 0 A 2664 0 U 2669 0 G 2670 0 U 2671 0 C 2672 0 A 2811 0 A 2816 0 G 2817 0 A 2818 0 C 2819 0 G 2829 0 U 2830 0 C 2831 0 C 2832 0 C 2833 0 C 2835 0 G 2836 0 U 2837 0 A 2838 0 G 2842 0 C 2844 0 G 2845 0 C 2846 0 A 2852 0 U 2853 0 A 2854 0 C 2897 0 G 2898 0 A 2899 0 G 2900 0 C 2901 0 2 1.94 1.94 137.9 -0.98 -0.58 11.7 75 7 3 0 1 3 2 0  U 533 0 C 534 0 G 535 0 A 536 0 C 541 0 A 542 0 G 564 0 A 565 0 U 614 0 G 615 0 U 616 0 C 617 0 G 618 0 G 1076 0 G 1089 0 A 1090 0 U 1091 0 A 1092 0 G 1093 0 C 1105 0 A 1106 0 G 1258 0 A 1259 0 G 1260 0 A 1261 0 C 1263 0 U 1264 0 G 1265 0 U 1266 0 C 1267 0 G 1284 0 U 1285 0 A 1286 0 A 1287 0 U 2078 0 G 2079 0 A 2675 0 A 2813 0 A 2814 0 G 2815 0 3 1.28 1.42 142.7 -1.01 -0.71 11.2 87 7 2 1 2 1 0 0  G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 A 331 0 G 332 0 A 340 0 C 341 0 G 564 0 A 565 0 G 1265 0 U 1266 0 C 1267 0 C 1268 0 G 1269 0 U 1270 0 C 1272 0 U 1279 0 A 1280 0 C 1281 0 U 1282 0 G 1283 0 G 1284 0 U 1285 0 G 1299 0 G 1300 0 C 1301 0 C 1303 0 C 1305 0 U 1306 0 A 1307 0 A 1308 0 G 1344 0 A 1345 0 U 1346 0 U 1347 0 A 1348 0 G 1349 0 U 1350 0 4 2.09 2.10 154.0 -0.73 -0.79 8.7 87 2 4 0 1 0 0 0  G 564 0 A 565 0 C 583 0 U 584 0 C 585 0 G 588 0 U 589 0 G 1100 0 G 1119 0 U 1120 0 G 1121 0 U 1122 0 A 1124 0 G 1131 0 G 1226 0 C 1227 0 C 1228 0 C 1229 0 A 1230 0 A 1231 0 U 1249 0 C 1250 0 C 1253 0 C 1254 0 A 1255 0 U 1266 0 U 2499 0 A 2553 0 U 2554 0 C 2555 0 C 2556 0 U 2557 0 C 2560 0 C 2561 0 G 2562 0 U 2563 0 C 2565 0 G 2570 0 C 2571 0 G 2572 0 G 2573 0 G 2574 0 C 2575 0 A 2776 0 G 2779 0 MG 8037 0 G 88 9 C 89 9 G 90 9 C 91 9 5 1.78 1.78 152.0 -1.05 -0.75 12.6 81 4 7 0 2 1 2 0  U 10 0 A 11 0 G 17 0 C 18 0 U 526 0 U 527 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 U 609 0 G 1323 0 U 2659 0 G 2660 0 U 2661 0 G 2662 0 A 2664 0 G 2668 0 U 2669 0 G 2670 0 U 2671 0 A 2811 0 A 2812 0 A 2816 0 G 2817 0 A 2818 0 C 2819 0 G 2829 0 C 2844 0 C 2912 0 A 2913 0 6 1.73 1.73 159.8 -0.92 -0.71 9.4 75 3 3 1 0 2 1 0  G 44 0 G 47 0 A 48 0 A 49 0 G 64 0 C 65 0 C 101 0 A 102 0 C 103 0 A 104 0 G 105 0 U 107 0 U 108 0 U 109 0 C 110 0 C 111 0 A 114 0 G 116 0 A 117 0 U 123 0 C 124 0 U 125 0 A 128 0 U 299 0 U 300 0 C 301 0 G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 316 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 A 331 0 G 332 0 A 340 0 C 341 0 U 346 0 A 347 0 C 443 0 C 444 0 U 445 0 G 446 0 A 447 0 U 673 0 A 1307 0 U 1673 0 N A 8525 0 7 2.05 2.05 166.5 -0.71 -0.74 7.8 84 2 4 1 2 1 3 0  G 1235 0 A 2083 0 C 2084 0 U 2550 0 U 2557 0 G 2558 0 C 2560 0 C 2561 0 G 2562 0 U 2563 0 C 2565 0 A 2569 0 G 2570 0 G 2578 0 U 2655 0 G 2658 0 U 2659 0 A 2664 0 U 2669 0 G 2670 0 U 2671 0 C 2672 0 A 2677 0 A 2678 0 G 2679 0 A 2680 0 A 2681 0 G 2683 0 A 2684 0 C 2685 0 C 2686 0 A 2703 0 C 2704 0 U 2705 0 C 2707 0 C 2769 0 G 2779 0 A 2800 0 A 2801 0 C 2802 0 C 2803 0 C 2804 0 A 2805 0 G 2809 0 A 2811 0 A 2812 0 A 2813 0 A 2816 0 G 2817 0 A 2818 0 C 2819 0 C 2844 0 8 1.84 1.84 169.2 -1.21 -0.80 13.2 81 5 9 2 1 0 1 0  U 10 0 A 11 0 G 17 0 C 18 0 U 526 0 U 527 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 U 609 0 G 1323 0 G 1728 0 A 1729 0 G 1730 0 C 2831 0 C 2832 0 C 2833 0 G 2834 0 C 2835 0 G 2836 0 U 2837 0 A 2838 0 A 2852 0 U 2853 0 A 2854 0 C 2897 0 G 2898 0 A 2899 0 G 2900 0 C 2901 0 A 2908 0 A 2910 0 C 2911 0 C 2912 0 9 1.75 1.75 192.2 -0.86 -0.74 9.1 79 3 2 0 0 1 0 0  G 203 0 A 234 0 C 235 0 A 236 0 G 237 0 C 271 0 A 272 0 G 273 0 A 285 0 U 286 0 C 295 0 G 296 0 U 297 0 C 298 0 G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 316 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 A 331 0 G 332 0 A 340 0 C 341 0 A 347 0 C 348 0 U 349 0 A 360 0 C 361 0 A 372 0 G 373 0 U 374 0 G 375 0 A 411 0 G 426 0 C 427 0 G 446 0 G 669 0 G 670 0 A 671 0 G 672 0 U 673 0 A 1307 0 10 1.78 1.78 195.0 -1.08 -0.68 12.2 83 9 4 0 2 1 0 0  C 18 0 U 19 0 G 20 0 C 29 0 C 31 0 C 87 0 G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 G 332 0 G 333 0 G 334 0 U 335 0 A 337 0 C 338 0 A 339 0 A 340 0 C 341 0 A 462 0 G 479 0 C 480 0 U 481 0 G 482 0 C 483 0 A 484 0 U 488 0 G 499 0 G 500 0 G 501 0 A 502 0 G 503 0 A 509 0 U 510 0 G 512 0 A 513 0 G 514 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 G 1322 0 G 1323 0 G 1337 0 U 1338 0 C 1342 0 A 1427 0 SR 8925 0 11 1.55 1.55 201.3 -0.68 -0.73 5.3 75 1 2 2 0 1 2 0  C 405 0 G 564 0 A 565 0 G 740 0 C 741 0 U 909 0 G 928 0 A 929 0 C 930 0 C 931 0 U 932 0 C 933 0 C 934 0 G 1031 0 A 1032 0 C 1033 0 G 1034 0 C 1035 0 G 1036 0 G 1037 0 G 1265 0 U 1266 0 C 1267 0 C 1268 0 G 1269 0 U 1270 0 A 1271 0 C 1272 0 U 1279 0 A 1280 0 U 1282 0 G 1283 0 G 1284 0 U 1285 0 U 1298 0 G 1299 0 A 1910 0 C 1911 0 A 1912 0 C 1913 0 C 1914 0 A 1921 0 A 1922 0 G 1923 0 A 1924 0 G 1925 0 C 2130 0 G 2131 0 A 2395 0 C 2396 0 G 2397 0 A 2398 0 G 2399 0 A 2429 0 A 2430 0 C 2431 0 C 2432 0 A 2455 0 A 2456 0 U 2457 0 U 2458 0 G 2459 0 A 2460 0 12 2.19 2.15 204.7 -1.01 -0.78 11.2 88 6 5 3 2 1 0 0  G 564 0 A 565 0 C 583 0 U 584 0 C 585 0 G 588 0 U 589 0 G 958 0 C 959 0 G 960 0 C 1000 0 U 1001 0 G 1002 0 U 1003 0 G 1223 0 G 1224 0 C 1251 0 A 1252 0 C 1253 0 C 1254 0 A 1255 0 U 1266 0 U 2330 0 C 2331 0 A 2332 0 C 2334 0 C 2335 0 G 2336 0 G 2337 0 G 2344 0 A 2345 0 C 2346 0 C 2347 0 C 2348 0 G 2349 0 G 2350 0 C 2351 0 G 2352 0 A 2353 0 C 15 9 C 67 9 G 68 9 A 77 9 U 79 9 A 80 9 G 88 9 C 95 9 C 96 9 U 97 9 A 105 9 U 106 9 C 107 9 C 108 9 13 1.81 1.81 203.3 -1.03 -0.72 11.9 78 6 4 0 1 1 0 0  C 18 0 U 19 0 G 20 0 C 31 0 G 44 0 G 47 0 A 48 0 A 49 0 C 62 0 U 63 0 G 64 0 C 65 0 C 85 0 A 86 0 A 102 0 C 103 0 A 104 0 G 105 0 U 107 0 U 108 0 U 109 0 C 110 0 C 111 0 A 114 0 G 116 0 A 117 0 U 123 0 C 124 0 U 125 0 A 128 0 C 443 0 C 444 0 C 461 0 A 462 0 G 479 0 C 480 0 U 488 0 G 499 0 G 500 0 G 501 0 A 502 0 G 503 0 A 509 0 U 510 0 G 512 0 A 513 0 G 514 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 G 1322 0 G 1323 0 G 1337 0 U 1338 0 A 1427 0 U 1673 0 NA 8525 0 SR 8925 0 14 1.74 1.74 214.7 -1.32 -0.70 15.3 80 11 10 2 3 1 1 0  C 29 0 C 31 0 C 87 0 G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 316 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 G 332 0 G 333 0 G 334 0 U 335 0 A 337 0 C 338 0 A 339 0 A 340 0 C 341 0 A 462 0 G 479 0 C 480 0 U 481 0 G 482 0 C 483 0 A 484 0 A 495 0 G 496 0 A 498 0 G 499 0 G 514 0 C 1342 0 A 1390 0 G 1391 0 A 1392 0 A 1393 0 A 1427 0 A 1434 0 G 1727 0 G 1728 0 A 1729 0 G 1730 0 C 2833 0 G 2834 0 C 2835 0 G 2836 0 U 2837 0 A 2838 0 A 2852 0 U 2853 0 A 2854 0 C 2897 0 G 2898 0 A 2899 0 G 2900 0 C 2901 0 SR 8991 0 15 1.80 1.80 220.1 -0.82 -0.76 9.8 87 4 7 1 2 0 1 0  U 10 0 A 11 0 G 17 0 C 18 0 U 526 0 U 527 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 U 609 0 G 1235 0 G 1323 0 A 2083 0 C 2084 0 U 2550 0 U 2557 0 G 2558 0 C 2560 0 C 2561 0 G 2562 0 U 2563 0 C 2565 0 A 2569 0 G 2570 0 G 2578 0 U 2655 0 G 2658 0 U 2659 0 G 2660 0 U 2661 0 G 2662 0 G 2668 0 U 2669 0 A 2677 0 A 2678 0 G 2679 0 A 2680 0 A 2681 0 G 2683 0 A 2684 0 C 2685 0 C 2686 0 A 2703 0 C 2704 0 U 2705 0 C 2707 0 C 2769 0 G 2779 0 A 2800 0 A 2801 0 C 2802 0 C 2803 0 C 2804 0 A 2805 0 G 2809 0 A 2812 0 A 2813 0 G 2829 0 C 2844 0 C 2912 0 A 2913 0 16 1.24 1.24 222.3 -0.95 -0.71 10.4 78 5 6 1 2 2 1 0  A 37 0 G 38 0 A 174 0 C 208 0 G 209 0 G 213 0 U 214 0 G 223 0 U 224 0 G 225 0 C 298 0 G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 316 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 A 331 0 G 332 0 A 340 0 C 341 0 A 347 0 C 440 0 G 446 0 A 447 0 U 647 0 G 648 0 U 649 0 C 650 0 U 651 0 G 652 0 A 666 0 C 667 0 C 668 0 A 671 0 U 673 0 A 674 0 U 675 0 A 686 0 G 690 0 G 739 0 G 740 0 C 741 0 G 742 0 A 758 0 C 759 0 A 1307 0 C 2317 0 C 2318 0 C 2319 0 U 2384 0 G 2385 0 U 2386 0 U 2387 0 G 2397 0 A 2398 0 G 2399 0 G 2400 0 A 2401 0 U 2419 0 G 2420 0 C 2427 0 NA 8503 C 17 1.81 1.91 225.0 -0.65 -0.78 6.2 80 4 1 1 0 0 1 0  G 13 0 C 14 0 A 536 0 C 538 0 G 539 0 C 541 0 A 542 0 G 564 0 A 565 0 C 613 0 U 614 0 G 615 0 U 616 0 C 617 0 G 618 0 G 1076 0 G 1089 0 A 1090 0 U 1091 0 A 1092 0 G 1093 0 C 1105 0 A 1106 0 G 1258 0 A 1259 0 G 1260 0 A 1261 0 C 1263 0 U 1264 0 G 1265 0 U 1266 0 C 1267 0 G 1284 0 U 1285 0 A 1286 0 A 1287 0 A 1729 0 G 1730 0 A 2062 0 U 2063 0 U 2078 0 G 2079 0 C 2084 0 A 2085 0 C 2086 0 C 2087 0 C 2651 0 U 2652 0 A 2653 0 C 2654 0 U 2655 0 G 2657 0 G 2658 0 U 2659 0 U 2669 0 G 2670 0 A 2812 0 G 2829 0 U 2830 0 C 2831 0 C 2832 0 C 2833 0 C 2835 0 G 2836 0 U 2837 0 A 2838 0 G 2842 0 C 2844 0 G 2845 0 C 2846 0 A 2852 0 U 2853 0 A 2854 0 C 2897 0 G 2898 0 A 2899 0 G 2900 0 C 2901 0 18 2.60 2.60 233.1 -0.66 -0.80 6.8 88 4 4 2 0 0 0 0  A 37 0 G 38 0 G 39 0 G 203 0 G 209 0 A 234 0 C 235 0 A 236 0 G 237 0 C 271 0 A 272 0 G 273 0 A 285 0 U 286 0 C 295 0 G 296 0 A 360 0 C 361 0 A 372 0 G 373 0 U 374 0 G 375 0 A 411 0 G 426 0 C 427 0 G 564 0 A 565 0 U 645 0 G 646 0 U 647 0 G 648 0 U 649 0 A 665 0 A 666 0 C 667 0 C 668 0 G 669 0 A 671 0 U 673 0 A 674 0 U 675 0 A 750 0 U 751 0 G 752 0 U 753 0 G 754 0 G 755 0 G 1265 0 U 1266 0 C 1267 0 C 1268 0 G 1269 0 U 1270 0 C 1272 0 U 1279 0 A 1280 0 C 1281 0 U 1282 0 G 1283 0 G 1284 0 U 1285 0 G 1299 0 G 1300 0 U 1347 0 A 1348 0 G 1349 0 U 1350 0 G 1351 0 C 1353 0 NA 8503 C 19 2.69 2.69 238.6 -0.82 -0.81 8.9 77 1 8 1 0 1 0 0  C 34 0 U 35 0 G 47 0 A 48 0 A 49 0 G 50 0 G 51 0 U 63 0 G 64 0 C 65 0 G 66 0 U 108 0 U 109 0 C 110 0 C 111 0 A 114 0 G 116 0 A 117 0 U 123 0 C 124 0 U 125 0 A 128 0 A 151 0 C 153 0 A 174 0 U 176 0 A 177 0 G 213 0 U 214 0 G 223 0 U 224 0 C 440 0 A 441 0 A 442 0 C 443 0 A 459 0 G 464 0 G 564 0 A 565 0 U 647 0 G 648 0 U 649 0 C 650 0 U 651 0 G 652 0 A 686 0 G 690 0 C 741 0 G 742 0 A 758 0 C 759 0 U 909 0 G 928 0 A 929 0 C 930 0 C 931 0 U 932 0 C 933 0 C 934 0 G 1031 0 A 1032 0 C 1033 0 G 1034 0 C 1035 0 G 1036 0 G 1037 0 G 1265 0 U 1266 0 C 1267 0 C 1268 0 G 1269 0 U 1270 0 A 1271 0 C 1272 0 U 1279 0 A 1280 0 U 1282 0 G 1283 0 G 1284 0 U 1285 0 U 1298 0 G 1299 0 U 1673 0 A 2395 0 C 2396 0 20 1.81 1.81 245.2 -1.15 -0.79 13.2 82 8 10 2 2 0 0 0  U 10 0 A 11 0 G 17 0 C 18 0 U 526 0 U 527 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 U 609 0 G 1323 0 U 1383 0 C 1384 0 G 1385 0 A 1393 0 C 1394 0 C 1396 0 C 1397 0 G 1398 0 A 1399 0 C 1400 0 G 1401 0 G 1402 0 G 1557 0 C 1558 0 A 1559 0 A 1716 0 C 1721 0 U 1722 0 G 1727 0 C 1808 0 G 1809 0 G 2730 0 G 2731 0 U 2732 0 C 2737 0 A 2741 0 G 2742 0 A 2743 0 C 2831 0 C 2832 0 C 2833 0 U 2866 0 G 2867 0 C 2868 0 A 2885 0 C 2886 0 C 2893 0 C 2894 0 A 2908 0 A 2910 0 C 2911 0 C 2912 0 21 1.64 1.64 244.7 -0.75 -0.74 6.1 81 3 2 3 0 1 2 0  G 564 0 A 565 0 G 740 0 C 741 0 U 909 0 G 928 0 A 929 0 C 930 0 C 931 0 U 932 0 C 933 0 C 934 0 G 1031 0 A 1032 0 C 1033 0 G 1034 0 C 1035 0 G 1036 0 G 1037 0 G 1265 0 U 1266 0 C 1267 0 C 1268 0 G 1269 0 U 1270 0 A 1271 0 C 1272 0 U 1279 0 A 1280 0 U 1282 0 G 1283 0 G 1284 0 U 1285 0 U 1298 0 G 1299 0 C 1856 0 A 1857 0 A 1858 0 A 1859 0 A 1909 0 A 1910 0 G 1925 0 G 2121 0 C 2122 0 A 2123 0 G 2124 0 G 2125 0 C 2126 0 U 2127 0 C 2241 0 U 2242 0 G 2254 0 A 2255 0 G 2256 0 G 2257 0 A 2260 0 C 2261 0 C 2262 0 U 2265 0 A 2266 0 G 2267 0 C 2268 0 G 2270 0 A 2395 0 C 2396 0 G 2397 0 A 2398 0 G 2399 0 A 2429 0 A 2430 0 C 2431 0 C 2432 0 A 2455 0 A 2456 0 U 2457 0 U 2458 0 G 2459 0 A 2460 0 22 1.79 1.79 248.7 -1.24 -0.80 14.2 84 8 12 3 1 0 0 0  U 10 0 A 11 0 G 17 0 C 18 0 U 526 0 U 527 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 U 609 0 G 787 0 G 1323 0 U 1383 0 C 1384 0 G 1385 0 A 1393 0 C 1394 0 C 1396 0 C 1397 0 G 1410 0 A 1411 0 C 1421 0 G 1438 0 G 1452 0 U 1488 0 G 1489 0 G 1490 0 A 1496 0 G 1497 0 U 1503 0 A 1504 0 U 1505 0 C 1534 0 G 1535 0 C 1617 0 C 1643 0 C 1644 0 U 1645 0 G 1646 0 G 1647 0 G 1655 0 C 1680 0 A 1685 0 C 1699 0 C 1700 0 C 1720 0 C 1721 0 U 1722 0 G 1727 0 C 2831 0 C 2832 0 C 2833 0 A 2908 0 A 2910 0 C 2911 0 C 2912 0 MG 8022 0 23 2.09 2.09 261.7 -0.67 -0.78 6.6 90 5 2 3 3 1 0 0  A 542 0 G 543 0 G 554 0 U 555 0 C 556 0 C 557 0 C 558 0 C 594 0 U 595 0 C 596 0 A 597 0 G 615 0 U 616 0 C 617 0 G 958 0 C 959 0 G 960 0 C 1000 0 U 1001 0 G 1002 0 U 1003 0 G 1076 0 G 1077 0 A 1092 0 G 1093 0 G 1100 0 U 1101 0 C 1105 0 A 1106 0 U 1122 0 A 1123 0 G 1223 0 G 1224 0 G 1239 0 U 1249 0 C 1250 0 C 1251 0 A 1252 0 C 1253 0 G 1258 0 A 1259 0 U 2330 0 C 2331 0 A 2332 0 C 2334 0 C 2335 0 G 2336 0 G 2337 0 G 2344 0 A 2345 0 C 2346 0 C 2347 0 C 2348 0 G 2349 0 G 2350 0 C 2351 0 G 2352 0 A 2353 0 C 15 9 C 67 9 G 68 9 A 77 9 U 79 9 A 80 9 G 88 9 C 95 9 C 96 9 U 97 9 A 105 9 U 106 9 C 107 9 C 108 9 24 1.88 1.88 266.4 -0.90 -0.79 10.1 77 5 8 1 1 1 1 0  U 146 0 G 147 0 A 148 0 G 149 0 G 150 0 C 153 0 C 154 0 A 174 0 U 176 0 A 177 0 U 178 0 G 180 0 G 181 0 G 182 0 A 183 0 C 208 0 G 213 0 U 214 0 G 223 0 U 224 0 C 440 0 G 564 0 A 565 0 U 647 0 G 648 0 U 649 0 C 650 0 U 651 0 G 652 0 A 686 0 G 690 0 C 741 0 G 742 0 A 758 0 C 759 0 U 909 0 G 928 0 A 929 0 C 930 0 C 931 0 U 932 0 C 933 0 C 934 0 G 1031 0 A 1032 0 C 1033 0 G 1034 0 C 1035 0 G 1036 0 G 1037 0 G 1265 0 U 1266 0 C 1267 0 C 1268 0 G 1269 0 U 1270 0 A 1271 0 C 1272 0 U 1279 0 A 1280 0 U 1282 0 G 1283 0 G 1284 0 U 1285 0 U 1298 0 G 1299 0 A 1458 0 A 1459 0 G 1460 0 U 1461 0 C 1462 0 U 1463 0 C 1464 0 A 1465 0 C 1466 0 C 1467 0 C 1472 0 U 1473 0 G 1475 0 A 1476 0 C 1477 0 U 1478 0 G 1479 0 U 1531 0 A 1533 0 C 1534 0 G 1655 0 A 1657 0 A 1658 0 C 1872 0 A 2395 0 C 2396 0 SR 8952 1 25 1.77 1.78 274.2 -1.08 -0.70 12.1 80 13 7 2 3 1 0 0  C 29 0 C 31 0 C 87 0 G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 316 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 G 332 0 G 333 0 G 334 0 U 335 0 A 337 0 C 338 0 A 339 0 A 340 0 C 341 0 A 462 0 G 479 0 C 480 0 U 481 0 G 482 0 C 483 0 A 484 0 A 495 0 G 496 0 A 498 0 G 499 0 G 514 0 C 1342 0 U 1383 0 C 1384 0 G 1385 0 G 1386 0 A 1390 0 G 1391 0 A 1392 0 A 1393 0 C 1394 0 C 1396 0 C 1397 0 G 1398 0 A 1399 0 C 1400 0 G 1401 0 G 1402 0 A 1427 0 A 1434 0 G 1557 0 C 1558 0 A 1559 0 A 1716 0 C 1721 0 U 1722 0 C 1808 0 G 1809 0 G 2730 0 G 2731 0 U 2732 0 C 2737 0 A 2741 0 G 2742 0 A 2743 0 U 2866 0 G 2867 0 C 2868 0 A 2885 0 C 2886 0 C 2893 0 C 2894 0 SR 8991 0 26 1.86 1.86 274.6 -0.87 -0.76 10.3 85 6 5 0 2 0 0 0  C 18 0 U 19 0 G 20 0 C 31 0 G 41 0 C 42 0 U 43 0 A 49 0 C 62 0 U 63 0 G 64 0 C 65 0 C 85 0 A 86 0 A 102 0 C 103 0 A 104 0 G 185 0 G 203 0 A 236 0 G 237 0 C 271 0 A 272 0 G 273 0 A 285 0 U 286 0 C 287 0 A 288 0 A 354 0 C 355 0 G 358 0 U 359 0 A 360 0 C 361 0 A 372 0 G 373 0 U 374 0 G 375 0 A 411 0 G 426 0 C 427 0 U 434 0 A 435 0 C 443 0 C 444 0 C 461 0 A 462 0 G 479 0 C 480 0 U 488 0 G 499 0 G 500 0 G 501 0 A 502 0 G 503 0 A 509 0 U 510 0 G 512 0 A 513 0 G 514 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 G 1322 0 G 1323 0 G 1337 0 U 1338 0 A 1427 0 SR 8925 0 27 1.79 1.79 280.4 -1.15 -0.65 11.8 83 12 2 4 3 1 0 0  C 29 0 C 31 0 C 87 0 G 307 0 C 309 0 U 310 0 C 311 0 U 312 0 G 314 0 A 316 0 A 317 0 U 318 0 A 319 0 G 320 0 A 321 0 G 322 0 C 323 0 C 330 0 G 332 0 G 333 0 G 334 0 U 335 0 A 337 0 C 338 0 A 339 0 A 340 0 C 341 0 A 462 0 A 466 0 G 467 0 A 476 0 G 479 0 C 480 0 U 481 0 G 482 0 C 483 0 A 484 0 G 514 0 U 845 0 C 1342 0 A 1427 0 C 1428 0 G 2099 0 A 2100 0 A 2103 0 C 2496 0 A 2497 0 C 2498 0 U 2527 0 U 2528 0 G 2540 0 C 2542 0 C 2555 0 C 2556 0 U 2557 0 C 2560 0 C 2561 0 G 2562 0 U 2563 0 C 2565 0 G 2570 0 C 2571 0 G 2572 0 G 2573 0 U 2589 0 U 2590 0 C 2591 0 G 2592 0 G 2602 0 G 2603 0 A 2604 0 G 2616 0 G 2618 0 UR3 2619 0 U 2620 0 A 2637 0 C 2644 0 U 2645 0 G 2779 0 SR 8990 0 28 1.82 1.82 280.7 -1.01 -0.75 10.9 83 10 6 5 1 1 0 0  C 18 0 U 19 0 G 20 0 A 466 0 G 467 0 U 468 0 A 476 0 U 488 0 G 500 0 G 501 0 A 502 0 G 503 0 A 509 0 U 510 0 G 512 0 A 513 0 G 514 0 U 548 0 A 549 0 C 550 0 A 551 0 A 552 0 G 553 0 G 554 0 G 604 0 U 768 0 C 769 0 C 770 0 G 771 0 G 772 0 A 773 0 A 844 0 U 866 0 A 867 0 G 868 0 G 869 0 A 882 0 U 883 0 G 887 0 U 888 0 C 889 0 G 1322 0 G 1323 0 G 1337 0 U 1338 0 A 1427 0 C 1428 0 G 1460 0 U 1461 0 C 1474 0 G 1475 0 A 1476 0 C 1477 0 U 1478 0 A 1689 0 C 1856 0 A 1857 0 A 1858 0 A 1859 0 C 1861 0 C 1862 0 G 1863 0 G 1867 0 G 1868 0 A 1869 0 C 1870 0 U 1871 0 C 1872 0 G 2125 0 C 2126 0 C 2241 0 U 2242 0 C 2247 0 C 2248 0 G 2254 0 A 2255 0 G 2256 0 G 2257 0 A 2260 0 C 2261 0 C 2262 0 SR 8925 0 SR 8930 A SR 8977 A 29 1.38 1.38 288.9 -0.71 -0.73 7.7 80 5 6 1 3 2 3 0  G 740 0 C 741 0 A 914 0 C 915 0 A 929 0 C 930 0 A 943 0 G 1034 0 C 1035 0 G 1036 0 G 1046 0 U 1047 0 G 1048 0 C 1049 0 C 1051 0 A 1058 0 G 1059 0 C 1060 0 C 1061 0 U 1062 0 G 1063 0 U 1064 0 G 1065 0 U 1066 0 C 1127 0 U 1128 0 C 1129 0 U 1130 0 G 1131 0 A 1231 0 A 1232 0 G 1235 0 A 1236 0 U 1237 0 C 1238 0 G 2068 0 A 2083 0 C 2084 0 C 2317 0 C 2318 0 C 2319 0 U 2384 0 G 2385 0 U 2386 0 U 2387 0 C 2388 0 U 2389 0 C 2393 0 A 2394 0 A 2395 0 C 2396 0 G 2397 0 A 2398 0 G 2399 0 G 2400 0 A 2401 0 U 2419 0 G 2420 0 C 2427 0 U 2492 0 C 2493 0 G 2524 0 G 2525 0 U 2550 0 C 2551 0 C 2552 0 A 2577 0 G 2578 0 U 2655 0 G 2658 0 U 2659 0 A 2664 0 U 2669 0 G 2670 0 U 2671 0 C 2672 0 A 2677 0 A 2678 0 G 2679 0 G 2809 0 A 2811 0 A 2812 0 A 2813 0 A 2816 0 G 2817 0 A 2818 0 C 2819 0 C 2844 0 C 91 9 G 92 9 A 93 9 30 2.34 2.34 323.0 -0.97 -0.80 10.1 81 10 8 3 1 0 0 0  U 10 0 A 11 0 U 12 0 G 13 0 C 14 0 C 523 0 A 524 0 G 525 0 U 526 0 A 536 0 C 538 0 G 539 0 C 541 0 A 542 0 G 564 0 A 565 0 C 613 0 U 614 0 G 615 0 U 616 0 C 617 0 G 618 0 G 1076 0 G 1089 0 A 1090 0 U 1091 0 A 1092 0 G 1093 0 C 1105 0 A 1106 0 G 1258 0 A 1259 0 G 1260 0 A 1261 0 C 1263 0 U 1264 0 G 1265 0 U 1266 0 C 1267 0 G 1284 0 U 1285 0 A 1286 0 A 1287 0 A 1367 0 U 1383 0 C 1384 0 G 1385 0 A 1393 0 C 1394 0 C 1396 0 C 1397 0 G 1398 0 A 1399 0 C 1400 0 G 1401 0 G 1402 0 G 1557 0 C 1558 0 A 1559 0 A 1716 0 C 1721 0 U 1722 0 G 1727 0 C 1808 0 G 1809 0 A 2062 0 U 2063 0 U 2078 0 G 2079 0 C 2651 0 G 2730 0 G 2731 0 U 2732 0 C 2737 0 A 2741 0 G 2742 0 A 2743 0 C 2831 0 C 2832 0 C 2833 0 U 2866 0 G 2867 0 C 2868 0 A 2885 0 C 2886 0 C 2893 0 C 2894 0 A 2908 0 A 2910 0 C 2911 0 C 2912 0 Residue-type_colouring Positive Negative Neutral Aliphatic Aromatic Pro & Gly Cysteine H,K,R D,E S,T,N,Q A,V,L,I,M F,Y,W P,G C Acknowledgement Pores were calculated by MOLE 2.0 program version 2.5.13.11.08 and visualized using Pymol 0.97rc.