PDBsum entry 3ca8

Structural genomics, unknown function

PDB id: 3ca8

Contents

Protein chains

261 a.a. *

Ligands

SO4 ×8

MPD ×14

Waters ×723

* Residue conservation analysis

PDB id:

3ca8

Name:

Structural genomics, unknown function

Title:

Crystal structure of escherichia coli ydcf, an s-adenosyl-l-methionine utilizing enzyme

Structure:

Protein ydcf. Chain: a, b. Engineered: yes

Source:

Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: ydcf, b1414, jw1411. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.80Å R-factor: 0.195 R-free: 0.238

Authors:

K.Lim,K.Chao,C.Lehmann,O.Herzberg,Structure 2 Function Project (S2f)

Key ref:

K.L.Chao et al. (2008). The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an alpha/beta-fold characteristic of nucleotide-utilizing enzymes. Proteins, 72, 506-509. PubMed id: 18393394 DOI: 10.1002/prot.22046

Date:

19-Feb-08 Release date: 06-May-08

Protein chains

P34209  (YDCF_ECOLI) -  Protein YdcF from Escherichia coli (strain K12)

Seq: 266 a.a.

Struc: 261 a.a.

Enzyme reactions

• Enzyme class: E.C.?

DOI no: 10.1002/prot.22046

Proteins 72:506-509 (2008)

PubMed id: 18393394

The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an alpha/beta-fold characteristic of nucleotide-utilizing enzymes.

K.L.Chao, K.Lim, C.Lehmann, V.Doseeva, A.J.Howard, F.P.Schwarz, O.Herzberg.

ABSTRACT

No abstract given.

Selected figure(s)

Figure 1.
Figure 1. Crystal structure of E. coli YdcF. (A) The overall fold with -helices colored in cyan and -strands in yellow. (B) Superposition of E. coli YdcF (cyan) and Methanococcus jannaschii. MJ0577 (yellow) with bound ATP. (C) Putative active site of E. coli YdcF. The ligand binding cavity and the surrounding residues are shown. Atomic colors used: carbon-gray; oxygen-red; nitrogen-blue; phosphate-magenta.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2008, 72, 506-509) copyright 2008.