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UniProt functional annotation for Q8PVT6 | ||
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| UniProt code: Q8PVT6. |
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| Organism: | |
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia). |
| Taxonomy: | |
Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina. |
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| Function: | |
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5- deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP. {ECO:0000255|HAMAP-Rule:MF_01257}. |
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| Catalytic activity: | |
Reaction=(2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8- hydroxy-5-deazariboflavin = GMP + H(+) + oxidized coenzyme F420-0; Xref=Rhea:RHEA:63444, ChEBI:CHEBI:15378, ChEBI:CHEBI:58115, ChEBI:CHEBI:59435, ChEBI:CHEBI:59904, ChEBI:CHEBI:59907; EC=2.7.8.28; Evidence={ECO:0000255|HAMAP-Rule:MF_01257}; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_01257}; |
| Pathway: | |
Cofactor biosynthesis; coenzyme F420 biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01257}. |
| Subunit: | |
Homodimer. {ECO:0000255|HAMAP-Rule:MF_01257}. |
| Similarity: | |
Belongs to the CofD family. {ECO:0000255|HAMAP- Rule:MF_01257}. |
Annotations taken from UniProtKB at the EBI.