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UniProt functional annotation for D0VWV4 | ||
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| UniProt code: D0VWV4. |
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| Organism: | |
Sus scrofa (Pig). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus. |
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| Function: | |
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). {ECO:0000269|PubMed:17480203}. |
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| Cofactor: | |
Name=heme; Xref=ChEBI:CHEBI:30413; Note=The heme is bound between the two transmembrane subunits SDHC and SDHD.; |
| Pathway: | |
Carbohydrate metabolism; tricarboxylic acid cycle. |
| Subunit: | |
Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD. {ECO:0000269|PubMed:15989954}. |
| Subcellular location: | |
Mitochondrion inner membrane {ECO:0000269|PubMed:17480203}; Multi-pass membrane protein {ECO:0000269|PubMed:17480203}. |
| Tissue specificity: | |
Detected in heart muscle (at protein level). {ECO:0000269|PubMed:17480203}. |
| Similarity: | |
Belongs to the cytochrome b560 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.