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UniProt functional annotation for Q5KX27 | ||
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| UniProt code: Q5KX27. |
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| Organism: | |
Geobacillus kaustophilus (strain HTA426). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus; Geobacillus thermoleovorans group. |
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| Function: | |
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. {ECO:0000255|HAMAP-Rule:MF_00152}. |
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| Catalytic activity: | |
Reaction=Endonucleolytic cleavage to 5'-phosphooligonucleotide end- products.; EC=3.1.21.2; Evidence={ECO:0000255|HAMAP-Rule:MF_00152}; |
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000255|HAMAP-Rule:MF_00152}; Note=Binds 3 Zn(2+) ions. {ECO:0000255|HAMAP-Rule:MF_00152}; |
| Similarity: | |
Belongs to the AP endonuclease 2 family. {ECO:0000255|HAMAP-Rule:MF_00152}. |
Annotations taken from UniProtKB at the EBI.