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UniProt functional annotation for Q6WY08 | ||
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| UniProt code: Q6WY08. |
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| Organism: | |
Agrocybe aegerita (Black poplar mushroom) (Agaricus aegerita). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; Agaricomycetidae; Agaricales; Bolbitiaceae; Agrocybe. |
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| Function: | |
Anti-tumor lectin with DNase activity. Inhibits the growth of several tumor cell lines in vitro. Induces lymphocyte infiltration and necrosis of tumor cells in a mouse tumor model. Induces apoptosis in HeLa cells. {ECO:0000269|PubMed:12757412}. |
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| Subunit: | |
Homodimer. {ECO:0000269|PubMed:12757412, ECO:0000269|PubMed:16051274}. |
| Tissue specificity: | |
Detected in the fruiting body. {ECO:0000269|PubMed:12757412}. |
Annotations taken from UniProtKB at the EBI.