UniProt functional annotation for Q9AIU0



	UniProt functional annotation for Q9AIU0

UniProt code: Q9AIU0.

Organism: Pseudomonas putida (strain DOT-T1E).

Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.

Function: Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics. {ECO:0000269|PubMed:11251828}.

Subunit: Homodimer. {ECO:0000250}.

Induction: Induced 4- to 8-fold in the presence of toluene; this is controlled by TtgX, a possible efflux pump global regulator. Induced by chloramphenicol and probably by tetracycline. {ECO:0000269|PubMed:14506010}.

Annotations taken from UniProtKB at the EBI.


Organism:		Pseudomonas putida (strain DOT-T1E).
Taxonomy:		Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.



Function:		Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics. {ECO:0000269\|PubMed:11251828}.


Subunit:		Homodimer. {ECO:0000250}.
Induction:		Induced 4- to 8-fold in the presence of toluene; this is controlled by TtgX, a possible efflux pump global regulator. Induced by chloramphenicol and probably by tetracycline. {ECO:0000269\|PubMed:14506010}.