UniProt functional annotation for P59213



	UniProt functional annotation for P59213

UniProt code: P59213.

Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).

Taxonomy: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus.

Function: Part of an ABC transporter complex involved in the uptake of maltodextrins. Binds glycogen-derived linear maltooligosaccharides increasing in size from maltotriose to maltooctaose with the highest affinity for maltotriose. Has a very weak affinity for maltose. Has also a very low affinity for maltotetraitol, indicating that the binding is selective for maltooligosaccharides with an intact reducing end. {ECO:0000269|PubMed:20497336}.

Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.

Induction: By maltose.

Disruption phenotype: Grows readily on glucose and maltotriose, but is not able to grow on glycogen. Deletion mutant is still able to depolymerize glycogen to some extent resulting in alpha- glucooligosaccharides increasing in size from maltotetraose to maltooctaose and larger oligosaccharides. In contrast to the wild-type cells, which almost completely deplete alpha-glucooligosaccharides up to eight glucose units in length, only partially deplete oligosaccharides of 9-11 glucose units in length and which have little to no ability to deplete oligosaccharides longer than 11 glucose units in length, the most abundant alpha-glucooligosaccharides produced by the deletion mutant are maltopentaose, maltohexaose, and maltoheptaose. {ECO:0000269|PubMed:20497336}.

Similarity: Belongs to the bacterial solute-binding protein 1 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.


Organism:		Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
Taxonomy:		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus.



Function:		Part of an ABC transporter complex involved in the uptake of maltodextrins. Binds glycogen-derived linear maltooligosaccharides increasing in size from maltotriose to maltooctaose with the highest affinity for maltotriose. Has a very weak affinity for maltose. Has also a very low affinity for maltotetraitol, indicating that the binding is selective for maltooligosaccharides with an intact reducing end. {ECO:0000269\|PubMed:20497336}.


Subcellular location:		Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Induction:		By maltose.
Disruption phenotype:		Grows readily on glucose and maltotriose, but is not able to grow on glycogen. Deletion mutant is still able to depolymerize glycogen to some extent resulting in alpha- glucooligosaccharides increasing in size from maltotetraose to maltooctaose and larger oligosaccharides. In contrast to the wild-type cells, which almost completely deplete alpha-glucooligosaccharides up to eight glucose units in length, only partially deplete oligosaccharides of 9-11 glucose units in length and which have little to no ability to deplete oligosaccharides longer than 11 glucose units in length, the most abundant alpha-glucooligosaccharides produced by the deletion mutant are maltopentaose, maltohexaose, and maltoheptaose. {ECO:0000269\|PubMed:20497336}.
Similarity:		Belongs to the bacterial solute-binding protein 1 family. {ECO:0000305}.