UniProt functional annotation for P03704



	UniProt functional annotation for P03704

UniProt code: P03704.

Organism: Escherichia phage T7 (Bacteriophage T7).

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus.

Function: Acts as an inhibitor of bacterial RNA polymerase by interacting with RpoC subunit and thus preventing promoter recognition by RpoE. Non-DNA-binding transcription factor that plays a role in the transcriptional switch that abolishes transcription of the viral early genes (class I) by the host RNA polymerase but allows transcription of late genes (class II and class III) by T7 RNA polymerase. {ECO:0000269|PubMed:10369763}.

Subunit: Interacts with host RpoC; this interaction inhibits host RNA polymerase activity. {ECO:0000269|PubMed:10369763}.

Annotations taken from UniProtKB at the EBI.


Organism:		Escherichia phage T7 (Bacteriophage T7).
Taxonomy:		Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus.



Function:		Acts as an inhibitor of bacterial RNA polymerase by interacting with RpoC subunit and thus preventing promoter recognition by RpoE. Non-DNA-binding transcription factor that plays a role in the transcriptional switch that abolishes transcription of the viral early genes (class I) by the host RNA polymerase but allows transcription of late genes (class II and class III) by T7 RNA polymerase. {ECO:0000269\|PubMed:10369763}.


Subunit:		Interacts with host RpoC; this interaction inhibits host RNA polymerase activity. {ECO:0000269\|PubMed:10369763}.