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UniProt functional annotation for P26648 | ||
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| UniProt code: P26648. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress. {ECO:0000255|HAMAP- Rule:MF_00915, ECO:0000269|PubMed:17766410}. |
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| Subcellular location: | |
Periplasm {ECO:0000255|HAMAP-Rule:MF_00915, ECO:0000269|PubMed:10593889, ECO:0000269|PubMed:19135451}. Note=Localizes to the division septum. Localization requires FtsZ, FtsQ, FtsL and FtsN. |
| Ptm: | |
Exported by the Tat system. The position of the signal peptide cleavage has been experimentally proven. Can also be exported by the Sec system. |
| Disruption phenotype: | |
Cells lacking this gene are sensitive to oxidative stress and DNA damage at high temperature. They also exhibit filamentation. {ECO:0000269|PubMed:17766410}. |
| Miscellaneous: | |
Is used as a model substrate in studies of the twin- arginine translocation (Tat) protein transport system. |
| Similarity: | |
Belongs to the FtsP family. {ECO:0000255|HAMAP- Rule:MF_00915}. |
Annotations taken from UniProtKB at the EBI.