PDBsum entry 2uxc Go to PDB code:  Tunnel analysis for: 2uxc calculated with MOLE 2.0 PDB id 2uxc Tunnels calculated on whole structure Tunnels calculated excluding ligands View options MOLEonline 2.0 manipulation and visualization with HETATM: without HETATM:   3 tunnels, coloured by tunnel radius 36 tunnels, coloured by tunnel radius 36 tunnels, coloured as in list below Tunnels are interior spaces connected with the protein surrounding. Only channels longer than 15 Å are shown. Tunnels Free R Length HPathy HPhob Polar Rel Mut Residue..type Ligands Radius 1 1.55 1.56 41.8 -0.33 -0.65 5.3 96 2 0 1 1 0 0 0  G 951 A U 952 A G 953 A G 954 A U 955 A U 956 A U 960 A U 961 A C 962 A G 971 A C 972 A G 973 A A 974 A A 975 A C 1223 A G 1224 A MG 2002 A MG 2109 A MG 2148 A MG 2159 A 2 1.54 1.55 43.2 -0.54 -0.61 6.7 87 2 0 1 1 1 0 0  G 951 A U 952 A G 953 A G 954 A U 955 A U 956 A U 960 A U 961 A C 962 A G 971 A C 972 A G 973 A A 974 A A 975 A C 1223 A G 1224 A MG 2002 A MG 2109 A MG 2148 A MG 2159 A 3 1.18 1.18 53.3 -0.47 -0.75 6.0 89 0 2 0 2 0 0 0  G 654 A A 655 A C 656 A C 744 A C 745 A G 755 A C 756 A G 823 A C 824 A G 825 A C 826 A G 851 A G 852 A G 876 A 4 1.34 1.34 54.6 -0.81 -0.53 9.5 82 6 0 1 2 1 1 0  U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A A 1225 A C 1226 A C 1322 A C 1362 A A 1363 A G 1365 A C 1366 A MG 2109 A MG 2176 A 5 1.35 1.35 56.0 -0.91 -0.52 10.0 79 6 0 1 2 2 1 0  U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A A 1225 A C 1226 A C 1322 A C 1362 A A 1363 A G 1365 A C 1366 A MG 2109 A MG 2176 A 6 1.31 1.31 56.7 -0.84 -0.62 11.2 89 7 0 1 2 0 0 0  G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A G 976 A A 977 A A 978 A C 980 A U 1257 A C 1359 A A 1360 A C 1361 A i:A G 1361 A A 1363 A G 1365 A C 1366 A MG 2030 A 7 1.32 1.32 58.1 -1.03 -0.60 12.6 86 7 0 1 2 1 0 0  G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A G 976 A A 977 A A 978 A C 980 A U 1257 A C 1359 A A 1360 A C 1361 A i:A G 1361 A A 1363 A G 1365 A C 1366 A MG 2030 A 8 1.18 1.18 70.6 -0.43 -0.77 4.8 88 0 1 0 1 0 0 0  G 654 A A 655 A C 656 A U 723 A G 724 A G 725 A G 727 A A 728 A A 729 A G 731 A U 743 A C 744 A G 755 A C 756 A G 818 A C 822 A G 823 A C 824 A G 825 A C 826 A G 853 A G 854 A G 855 A C 856 A G 876 A U 1528 A MG 2129 A K 2218 A 9 1.20 1.20 71.2 -0.85 -0.69 10.1 79 3 1 0 1 0 1 0  G 654 A A 655 A C 656 A G 657 A G 658 A U 659 A G 660 A G 661 A G 662 A U 743 A C 744 A C 745 A G 755 A C 756 A G 823 A C 824 A G 825 A C 826 A G 876 A 10 1.72 1.73 72.2 -1.18 -0.60 14.4 82 7 1 2 3 0 1 0  A 949 A U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A U 1307 A G 1311 A G 1312 A C 1320 A C 1321 A G 1323 A A 1324 A C 1325 A C 1362 A A 1363 A G 1365 A C 1366 A MG 2184 A 11 1.71 1.75 73.7 -1.26 -0.59 14.8 80 7 1 2 3 1 1 0  A 949 A U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A U 1307 A G 1311 A G 1312 A C 1320 A C 1321 A G 1323 A A 1324 A C 1325 A C 1362 A A 1363 A G 1365 A C 1366 A MG 2184 A 12 1.35 1.44 80.9 -1.33 -0.64 15.2 85 8 1 2 1 1 0 0  A 949 A U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A U 1301 A G 1304 A G 1305 A A 1306 A U 1307 A U 1308 A A 1324 A A 1329 A U 1330 A G 1331 A C 1362 A A 1363 A G 1365 A C 1366 A MG 2184 A 13 1.18 1.17 80.5 -1.18 -0.59 14.2 82 6 2 1 2 1 0 0  U 580 A G 581 A A 583 A G 584 A G 654 A A 655 A C 656 A U 743 A G 755 A C 756 A U 757 A G 823 A C 824 A G 825 A C 826 A G 876 A MG 2059 A 14 1.20 1.20 81.1 -0.55 -0.75 6.4 86 2 1 0 1 0 0 0  G 576 A G 577 A C 578 A G 579 A U 580 A G 654 A A 655 A C 656 A A 728 A U 743 A G 755 A C 756 A G 758 A G 761 A C 762 A G 763 A C 764 A G 765 A C 810 A C 812 A C 822 A G 823 A C 824 A G 825 A C 826 A G 876 A C 897 A G 898 A C 904 A K 2197 A 15 1.35 1.49 82.3 -1.36 -0.64 15.2 83 8 1 2 1 2 0 0  A 949 A U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A U 1301 A G 1304 A G 1305 A A 1306 A U 1307 A U 1308 A A 1324 A A 1329 A U 1330 A G 1331 A C 1362 A A 1363 A G 1365 A C 1366 A MG 2184 A 16 1.71 1.74 84.1 -0.45 -0.73 5.2 92 4 0 1 1 0 0 0  A 949 A U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A G 1258 A C 1259 A C 1260 A C 1270 A G 1271 A G 1272 A G 1273 A C 1284 A C 1314 A U 1315 A A 1324 A C 1325 A G 1356 A C 1361 A i:A G 1361 A C 1362 A A 1363 A U 1364 A G 1365 A C 1366 A MG 2184 A 17 1.74 1.83 85.6 -0.52 -0.71 5.6 86 4 0 1 1 1 0 0  A 949 A U 950 A G 951 A G 971 A C 972 A G 973 A A 974 A A 975 A A 977 A G 1224 A G 1258 A C 1259 A C 1260 A C 1270 A G 1271 A G 1272 A G 1273 A C 1284 A C 1314 A U 1315 A A 1324 A C 1325 A G 1356 A C 1361 A i:A G 1361 A C 1362 A A 1363 A U 1364 A G 1365 A C 1366 A MG 2184 A 18 1.19 1.19 91.0 -1.06 -0.63 11.4 75 5 2 0 0 1 0 0  G 947 A C 948 A C 1234 A U 1235 A A 1236 A C 1237 A G 1241 A C 1242 A A 1289 A G 1290 A G 1291 A G 1293 A G 1294 A G 1304 A G 1305 A A 1306 A C 1325 A A 1332 A A 1333 A G 1334 A U 1351 A C 1352 A G 1353 A C 1354 A G 1355 A G 1356 A C 1362 A A 1363 A U 1364 A G 1365 A MG 2136 A MG 2138 A 19 1.16 1.32 94.6 -0.33 -0.39 6.8 78 3 0 0 5 2 0 0  A 120 A C 121 A G 122 A C 233 A C 235 A G 236 A U 252 A C 267 A C 268 A C 283 A C 314 A A 315 A G 316 A G 319 A C 320 A C 328 A A 329 A G 333 A C 334 A C 335 A C 336 A C 337 A A 338 A C 339 A G 347 A G 350 A G 351 A MG 2089 A 20 1.18 1.17 98.2 -0.50 -0.76 5.7 84 2 1 0 1 0 0 0  U 244 A C 245 A A 246 A G 576 A C 578 A G 579 A U 580 A G 654 A A 655 A C 656 A A 728 A U 743 A G 755 A C 756 A G 758 A G 760 A G 761 A C 762 A C 822 A G 823 A C 824 A G 825 A C 826 A G 876 A G 894 A G 895 A C 896 A C 904 A U 905 A G 1476 A C 1477 A K 2197 A 21 1.23 2.32 106.2 -0.32 -0.27 9.3 78 5 2 0 8 3 1 0  A 120 A C 121 A C 235 A G 236 A C 237 A G 238 A U 239 A C 240 A C 277 A G 281 A A 282 A G 301 A G 302 A G 593 A G 594 A C 596 A G 597 A A 632 A G 633 A C 634 A G 635 A U 646 A C 647 A A 648 A 22 1.18 1.18 107.3 -1.30 -0.70 15.9 77 6 5 0 1 1 1 0  G 7 A G 566 A G 567 A G 568 A C 569 A G 654 A A 655 A C 656 A U 743 A C 744 A G 755 A C 756 A G 821 A C 822 A G 823 A C 824 A G 825 A C 826 A G 853 A U 871 A A 872 A A 873 A G 874 A C 875 A G 876 A C 877 A 23 1.26 1.24 109.0 -0.28 -0.58 7.3 83 3 2 0 6 0 1 0  U 5 A G 299 A A 300 A U 565 A G 567 A G 568 A C 569 A G 630 A G 631 A G 654 A A 655 A C 656 A U 743 A C 744 A G 755 A C 756 A G 821 A C 822 A G 823 A C 824 A G 825 A C 826 A G 853 A U 871 A A 872 A A 873 A G 874 A G 876 A C 877 A C 879 A MG 2060 A 24 1.21 1.39 122.3 -0.54 -0.47 8.7 76 6 0 0 4 2 0 0  A 120 A C 121 A G 122 A U 133 A A 134 A G 146 A G 147 A G 148 A A 171 A A 172 A U 173 A C 175 A C 176 A A 196 A A 197 A G 198 A U 222 A U 223 A C 233 A C 235 A G 236 A U 252 A U 261 A A 262 A A 263 A G 265 A C 267 A C 268 A C 283 A C 314 A G 319 A C 320 A G 324 A A 325 A G 326 A A 327 A C 328 A MG 2034 A MG 2068 A MG 2152 A MG 2191 A 25 1.18 1.18 121.9 -1.29 -0.68 14.8 79 5 7 2 1 2 1 0  G 568 A C 569 A G 654 A A 655 A C 656 A U 743 A C 744 A G 755 A C 756 A G 821 A C 822 A G 823 A C 824 A G 825 A C 826 A G 853 A G 861 A C 862 A U 871 A A 872 A A 873 A G 874 A C 875 A G 876 A C 877 A U 1078 A MG 2175 A 26 1.22 2.25 124.6 -0.50 -0.53 7.7 76 3 1 0 4 2 0 0  A 120 A C 121 A C 235 A G 236 A U 239 A C 240 A C 241 A C 242 A A 243 A C 277 A G 281 A A 282 A A 573 A A 574 A C 883 A U 884 A G 885 A G 886 A G 887 A G 888 A A 889 A G 890 A U 891 A A 892 A G 902 A G 906 A A 907 A A 908 A G 1405 A G 1486 A G 1487 A U 1510 A G 1511 A U 1512 A A 1519 A G 1520 A 27 1.21 2.22 134.0 -0.44 -0.35 10.1 81 5 1 0 10 2 1 0  A 120 A C 121 A C 235 A G 236 A G 238 A U 239 A C 240 A C 277 A G 281 A A 282 A A 300 A G 301 A G 302 A C 564 A U 565 A G 567 A G 568 A C 569 A A 632 A G 821 A C 822 A G 823 A C 824 A G 825 A C 826 A U 827 A G 851 A G 852 A U 870 A U 871 A A 872 A A 873 A G 874 A G 876 A C 877 A C 879 A MG 2060 A 28 1.34 1.34 136.4 -0.56 -0.58 6.6 82 6 0 2 5 2 0 0  A 120 A C 121 A C 235 A G 236 A U 239 A C 240 A C 241 A C 242 A A 243 A U 244 A C 277 A G 281 A A 282 A G 668 A A 716 A C 717 A G 718 A C 719 A C 732 A A 733 A G 760 A G 761 A C 762 A G 763 A C 764 A G 765 A A 766 A A 767 A C 805 A C 806 A A 807 A C 808 A G 809 A C 810 A C 811 A C 812 A C 882 A G 895 A C 896 A C 897 A G 903 A C 904 A U 905 A G 1525 A G 1526 A MG 2157 A 29 1.20 1.46 137.9 -1.12 -0.47 15.0 73 8 6 1 5 4 2 0  G 7 A A 120 A C 121 A C 235 A G 236 A G 238 A U 239 A C 240 A C 277 A G 281 A A 282 A G 299 A A 300 A G 301 A G 302 A C 564 A U 565 A G 566 A A 632 A G 858 A A 859 A A 860 A G 861 A C 862 A U 863 A C 866 A G 867 A C 1076 A G 1077 A U 1078 A MG 2020 A 30 1.34 1.34 154.0 -0.63 -0.76 6.9 81 5 1 0 1 0 0 0  A 119 A A 120 A C 121 A U 239 A C 240 A C 241 A C 242 A A 243 A U 244 A G 251 A U 252 A C 277 A G 281 A A 282 A C 283 A G 284 A G 319 A G 576 A C 578 A G 579 A U 580 A G 654 A A 655 A C 656 A A 728 A U 743 A G 755 A C 756 A G 758 A G 760 A G 761 A C 762 A C 822 A G 823 A C 824 A G 825 A C 826 A G 876 A C 882 A C 904 A U 905 A C 1426 A U 1427 A A 1428 A C 1429 A C 1466 A G 1467 A A 1468 A K 2197 A 31 1.18 1.51 164.6 -0.85 -0.33 13.2 73 12 1 1 9 6 1 0  G 6 A G 28 A G 29 A A 120 A C 121 A C 235 A G 236 A G 238 A U 239 A C 240 A C 277 A G 281 A A 282 A G 292 A G 293 A U 296 A G 297 A G 299 A A 300 A G 301 A G 302 A C 400 A G 546 A A 547 A G 548 A C 549 A G 610 A A 611 A G 630 A G 631 A A 632 A MG 2127 A K 2194 A K 2201 A 32 1.20 2.76 20.9 0.11 0.02 12.0 83 1 1 1 7 0 0 0   33 1.20 2.96 27.3 -0.26 0.04 19.6 82 2 2 0 5 1 0 0   34 1.61 1.66 20.9 -1.28 -0.78 9.0 81 1 1 1 1 0 0 0  G 254 A A 273 A G 275 A 35 1.61 1.66 21.5 -1.26 -0.78 8.9 81 1 1 1 1 0 0 0  G 254 A A 273 A 36 1.18 1.68 17.5 0.57 0.40 18.1 82 1 2 1 7 0 0 0   Residue-type_colouring Positive Negative Neutral Aliphatic Aromatic Pro & Gly Cysteine H,K,R D,E S,T,N,Q A,V,L,I,M F,Y,W P,G C Acknowledgement Tunnels were calculated by MOLE 2.0 program version 2.5.13.11.08 and visualized using Pymol 0.97rc.