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UniProt functional annotation for P07309 | ||
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| UniProt code: P07309. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. |
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| Subunit: | |
Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4 (By similarity). {ECO:0000250}. |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Detected in plasma (at protein level). Detected in liver. |
| Miscellaneous: | |
The mouse protein shows increased stability and much reduced propensity to form amyloid fibrils, compared to the human protein. |
| Similarity: | |
Belongs to the transthyretin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.