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UniProt functional annotation for P07360 | ||
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| UniProt code: P07360. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. |
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| Subunit: | |
C8 is composed of three chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. |
| Subcellular location: | |
Secreted. |
| Similarity: | |
Belongs to the calycin superfamily. Lipocalin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.