| UniProt functional annotation for P0A1F6 | |||
| UniProt code: P0A1F6. |
| Organism: | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). | |
| Taxonomy: | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella. | |
| Function: | Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). {ECO:0000250}. | |
| Catalytic activity: | Reaction=phosphate + uridine = alpha-D-ribose 1-phosphate + uracil; Xref=Rhea:RHEA:24388, ChEBI:CHEBI:16704, ChEBI:CHEBI:17568, ChEBI:CHEBI:43474, ChEBI:CHEBI:57720; EC=2.4.2.3; | |
| Pathway: | Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1. | |
| Subunit: | Homohexamer. {ECO:0000250}. | |
| Subcellular location: | Cytoplasm {ECO:0000250}. | |
| Similarity: | Belongs to the PNP/UDP phosphorylase family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.