UniProt functional annotation for P0A1F6

UniProt code: P0A1F6.

Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella.
 
Function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). {ECO:0000250}.
 
Catalytic activity: Reaction=phosphate + uridine = alpha-D-ribose 1-phosphate + uracil; Xref=Rhea:RHEA:24388, ChEBI:CHEBI:16704, ChEBI:CHEBI:17568, ChEBI:CHEBI:43474, ChEBI:CHEBI:57720; EC=2.4.2.3;
Pathway: Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.
Subunit: Homohexamer. {ECO:0000250}.
Subcellular location: Cytoplasm {ECO:0000250}.
Similarity: Belongs to the PNP/UDP phosphorylase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.