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UniProt functional annotation for P60624 | ||
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| UniProt code: P60624. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. It is not thought to be involved in the functions of the mature 50S subunit in vitro. {ECO:0000269|PubMed:3298242, ECO:0000269|PubMed:357435, ECO:0000269|PubMed:6760192}. |
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| Function: | |
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. {ECO:0000269|PubMed:16292303, ECO:0000269|PubMed:357435}. |
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| Subunit: | |
Part of the 50S ribosomal subunit (PubMed:391595, PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:25310980, PubMed:24844575, PubMed:27934701, PubMed:27906160, PubMed:27906161). Might contact the SecYEG translocation complex when it is docked with the ribosome. {ECO:0000269|PubMed:10094780, ECO:0000269|PubMed:12809609, ECO:0000269|PubMed:16272117, ECO:0000269|PubMed:24844575, ECO:0000269|PubMed:25310980, ECO:0000269|PubMed:27906160, ECO:0000269|PubMed:27906161, ECO:0000269|PubMed:27934701, ECO:0000269|PubMed:6222285, ECO:0000305|PubMed:16292303}. |
| Mass spectrometry: | |
Mass=11186.5; Method=MALDI; Evidence={ECO:0000269|PubMed:10094780}; |
| Similarity: | |
Belongs to the universal ribosomal protein uL24 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.