UniProt functional annotation for P0ADZ0



	UniProt functional annotation for P0ADZ0

UniProt codes: P0ADZ0, P02424.

Organism: Escherichia coli (strain K12).

Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.

Function: One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor (PubMed:12226666) for Ffh binding to the ribosome (SRP54, PubMed:12756233 and PubMed:12702815) and to nascent polypeptide chains (PubMed:12756233). {ECO:0000269|PubMed:12226666, ECO:0000269|PubMed:12702815, ECO:0000269|PubMed:12756233, ECO:0000269|PubMed:3298242, ECO:0000269|PubMed:6170935}.

Subunit: Part of the 50S ribosomal subunit (PubMed:391594, PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:21499241, PubMed:25310980, PubMed:24844575, PubMed:27934701, PubMed:27906160, PubMed:27906161). Contacts protein L29 and trigger factor. Might also contact SecE and probably does contact SecG and SecY when the SecYEG translocation complex is docked with the ribosome (PubMed:16292303). {ECO:0000269|PubMed:10094780, ECO:0000269|PubMed:12226666, ECO:0000269|PubMed:12756233, ECO:0000269|PubMed:12809609, ECO:0000269|PubMed:16272117, ECO:0000269|PubMed:16292303, ECO:0000269|PubMed:21499241, ECO:0000269|PubMed:24844575, ECO:0000269|PubMed:25310980, ECO:0000269|PubMed:2665813, ECO:0000269|PubMed:27906160, ECO:0000269|PubMed:27906161, ECO:0000269|PubMed:27934701, ECO:0000305|PubMed:16292303}.

Mass spectrometry: Mass=11198.0; Method=MALDI; Evidence={ECO:0000269|PubMed:10094780};

Similarity: Belongs to the universal ribosomal protein uL23 family. {ECO:0000255|HAMAP-Rule:MF_01369}.

Annotations taken from UniProtKB at the EBI.


Organism:		Escherichia coli (strain K12).
Taxonomy:		Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.



Function:		One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor (PubMed:12226666) for Ffh binding to the ribosome (SRP54, PubMed:12756233 and PubMed:12702815) and to nascent polypeptide chains (PubMed:12756233). {ECO:0000269\|PubMed:12226666, ECO:0000269\|PubMed:12702815, ECO:0000269\|PubMed:12756233, ECO:0000269\|PubMed:3298242, ECO:0000269\|PubMed:6170935}.


Subunit:		Part of the 50S ribosomal subunit (PubMed:391594, PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:21499241, PubMed:25310980, PubMed:24844575, PubMed:27934701, PubMed:27906160, PubMed:27906161). Contacts protein L29 and trigger factor. Might also contact SecE and probably does contact SecG and SecY when the SecYEG translocation complex is docked with the ribosome (PubMed:16292303). {ECO:0000269\|PubMed:10094780, ECO:0000269\|PubMed:12226666, ECO:0000269\|PubMed:12756233, ECO:0000269\|PubMed:12809609, ECO:0000269\|PubMed:16272117, ECO:0000269\|PubMed:16292303, ECO:0000269\|PubMed:21499241, ECO:0000269\|PubMed:24844575, ECO:0000269\|PubMed:25310980, ECO:0000269\|PubMed:2665813, ECO:0000269\|PubMed:27906160, ECO:0000269\|PubMed:27906161, ECO:0000269\|PubMed:27934701, ECO:0000305\|PubMed:16292303}.
Mass spectrometry:		Mass=11198.0; Method=MALDI; Evidence={ECO:0000269\|PubMed:10094780};
Similarity:		Belongs to the universal ribosomal protein uL23 family. {ECO:0000255\|HAMAP-Rule:MF_01369}.