UniProt functional annotation for P0AG63

UniProt codes: P0AG63, P02373.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA (PubMed:4598121). Also plays a role in translational accuracy; neamine-resistant ribosomes show reduced neamine-induced misreading in vitro (PubMed:765484, PubMed:781296). {ECO:0000269|PubMed:4598121, ECO:0000269|PubMed:765484, ECO:0000269|PubMed:781296}.
 
Subunit: Part of the 30S ribosomal subunit (PubMed:344065, PubMed:7556101, PubMed:4598121, PubMed:10094780, PubMed:12244297, PubMed:12809609, PubMed:16272117, PubMed:27934701, PubMed:27906160, PubMed:27906161). {ECO:0000269|PubMed:10094780, ECO:0000269|PubMed:12244297, ECO:0000269|PubMed:12809609, ECO:0000269|PubMed:16272117, ECO:0000269|PubMed:27906160, ECO:0000269|PubMed:27906161, ECO:0000269|PubMed:27934701, ECO:0000269|PubMed:344065, ECO:0000269|PubMed:4598121, ECO:0000269|PubMed:7556101}.
Mass spectrometry: Mass=9573.0; Method=MALDI; Evidence={ECO:0000269|PubMed:10094780};
Miscellaneous: The strain missing both S17 and L29 grows very slowly and has a rather unstable temperature-sensitive phenotype. {ECO:0000269|PubMed:3926498}.
Similarity: Belongs to the universal ribosomal protein uS17 family. {ECO:0000255|HAMAP-Rule:MF_01345}.

Annotations taken from UniProtKB at the EBI.