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UniProt functional annotation for P61889 | ||
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| UniProt code: P61889. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Catalyzes the reversible oxidation of malate to oxaloacetate. {ECO:0000255|HAMAP-Rule:MF_01516, ECO:0000269|PubMed:2993232, ECO:0000269|PubMed:7028159}. |
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| Catalytic activity: | |
Reaction=(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate; Xref=Rhea:RHEA:21432, ChEBI:CHEBI:15378, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.37; Evidence={ECO:0000255|HAMAP-Rule:MF_01516, ECO:0000269|PubMed:2993232, ECO:0000269|PubMed:7028159}; |
| Subunit: | |
Homodimer. {ECO:0000255|HAMAP-Rule:MF_01516, ECO:0000269|PubMed:11389141, ECO:0000269|PubMed:1507230, ECO:0000269|PubMed:7028159, ECO:0000269|PubMed:8331658}. |
| Similarity: | |
Belongs to the LDH/MDH superfamily. MDH type 1 family. {ECO:0000255|HAMAP-Rule:MF_01516, ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.