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UniProt functional annotation for P81065 | ||
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| UniProt code: P81065. |
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| Organism: | |
Ochrobactrum anthropi. |
| Taxonomy: | |
Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Ochrobactrum. |
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| Function: | |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. |
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| Catalytic activity: | |
Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18; Evidence={ECO:0000269|PubMed:18076047}; |
| Biophysicochemical properties: | |
Kinetic parameters: KM=0.132 mM for glutathione {ECO:0000269|PubMed:18076047}; |
| Subunit: | |
Homodimer. {ECO:0000250}. |
| Subcellular location: | |
Cytoplasm {ECO:0000250}. |
| Similarity: | |
Belongs to the GST superfamily. Beta family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.