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PDBsum entry 2pab
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Transport (thyroxine,retinol) in serum
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PDB id
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2pab
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Contents |
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* Residue conservation analysis
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References listed in PDB file
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Key reference
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Title
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Structure of prealbumin: secondary, Tertiary and quaternary interactions determined by fourier refinement at 1.8 a.
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Authors
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C.C.Blake,
M.J.Geisow,
S.J.Oatley,
B.Rérat,
C.Rérat.
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Ref.
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J Mol Biol, 1978,
121,
339-356.
[DOI no: ]
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PubMed id
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Abstract
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No abstract given.
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Figure 7.
FIG. 7. Stereo drawg of he nternal water structure. Thick and thin lines isinuih the 2
rnonorners n the dimer. a) Shows the hydrogen ond network involving he water molecules,
and b) their local nvironment in he imer.
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Figure 11.
FIQ. 11. Stereo drawing of the association of he DAGHH''A'U' hot% from ach ime1
looking down the axis with own and acmss. It, s n quivalent view t,o ig. (a) and the
right-hand diagram of Fig. 9. The imer-dimw inbfaces arc ocated at, he edges of his truct,nrr.
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The above figures are
reprinted
by permission from Elsevier:
J Mol Biol
(1978,
121,
339-356)
copyright 1978.
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Secondary reference #1
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Title
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Protein-Dna and protein-Hormone interactions in prealbumin: a model of the thyroid hormone nuclear receptor?
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Authors
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C.C.Blake,
S.J.Oatley.
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Ref.
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Nature, 1977,
268,
115-120.
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PubMed id
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Secondary reference #2
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Title
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Strjcture of human plasma prealbumin at 2-5 a resolution. A preliminary report on the polypeptide chain conformation, Quaternary structure and thyroxine binding.
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Authors
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C.C.Blake,
M.J.Geisow,
I.D.Swan,
C.Rerat,
B.Rerat.
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Ref.
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J Mol Biol, 1974,
88,
1.
[DOI no: ]
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PubMed id
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Figure 6.
FIG. 6. A stereo-view of the prealbumin tetramer down the molecular y'axis. N - residue 10;
C E reidue 126. T--- T represents the tw di-iodotyrosyl residues of thyroxine located on
the molecular c-axis.
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Figure 7.
FIG. 7. A stereo-view of the prealbumin tetramer looking down the molecular z-axis, shown
by the dot, with the molecular x' and y'-&is horizontal and vertical, respectively, The thyroxine
binding sites are superposed along the zaxis.
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The above figures are
reproduced from the cited reference
with permission from Elsevier
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Secondary reference #3
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Title
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An X-Ray study of the subunit structure of prealbumin.
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Authors
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C.C.Blake,
I.D.Swan,
C.Rerat,
J.Berthou,
A.Laurent,
B.Rerat.
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Ref.
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J Mol Biol, 1971,
61,
217-224.
[DOI no: ]
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PubMed id
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Figure 1.
FIG. . The ymmetry relations of a) 222, (b) P212,2 and (c) 222 projectd own the c-axis.
he origin of 21212 has been hifted from ts onventional position to O,O,) to show its relation-
hip o I222 ore learly.
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The above figure is
reproduced from the cited reference
with permission from Elsevier
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