|
|
||
|
|
|
|
|
UniProt functional annotation for P78789 | ||
|
|
|
|
|
|
||
| UniProt code: P78789. |
|
||
| Organism: | |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. |
|
||
|
||
| Function: | |
Beta subunit of AMP-activated protein kinase (AMPK), which is required for transcriptional, metabolic, and developmental adaptations in response to glucose limitation. Has a structural role, mediating heterotrimer formation, and a regulatory role, defining carbon source- regulated subcellular location and substrate specificity of the AMPK kinase complex. {ECO:0000250|UniProtKB:P34164}. |
|
||
| Subunit: | |
AMPK is a heterotrimer of an alpha catalytic subunit (ssp2), a beta (amk2) and a gamma non-catalytic subunits (cbs2). The beta subunit serves as a bridge between the catalytic and the regulatory subunit. {ECO:0000250|UniProtKB:P34164}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:16823372}. |
| Similarity: | |
Belongs to the 5'-AMP-activated protein kinase beta subunit family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=BAA13800.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.