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PDBsum entry 2oju
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Isomerase/immunosuppressant
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PDB id
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2oju
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Isomerase/immunosuppressant
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Title:
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X-ray structure of complex of human cyclophilin j with cyclosporin a
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Structure:
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Peptidyl-prolyl cis-trans isomerase-like 3. Chain: a, b. Synonym: ppiase, rotamase, cyclophilin-like protein ppil3, cyclophilin j, cypj. Engineered: yes. Cyclosporin a. Chain: c, d. Synonym: ciclosporin, ciclosporine. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Tissue: fetal brain. Gene: ppil3b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Tolypocladium inflatum.
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Resolution:
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2.40Å
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R-factor:
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0.193
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R-free:
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0.237
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Authors:
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Z.Xia,L.Huang
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Key ref:
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J.Chen
et al.
Targeting cyclophilin j, A novel peptidyl-Prolyl isomerase, Can induce cellular g1/s arrest and repress the growth of hepatocellular carcinoma.
To be published,
.
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Date:
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14-Jan-07
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Release date:
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22-Jan-08
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PROCHECK
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Headers
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References
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Enzyme class:
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Chains A, B:
E.C.5.2.1.8
- peptidylprolyl isomerase.
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Reaction:
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[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)
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Peptidylproline (omega=180)
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=
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peptidylproline (omega=0)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
