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UniProt functional annotation for P12281 | ||
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| UniProt code: P12281. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. {ECO:0000269|PubMed:15632135}. |
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| Catalytic activity: | |
Reaction=adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo- molybdopterin; Xref=Rhea:RHEA:35047, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:36264, ChEBI:CHEBI:62727, ChEBI:CHEBI:71302, ChEBI:CHEBI:456215; EC=2.10.1.1; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:11428898}; Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000269|PubMed:11428898}; |
| Pathway: | |
Cofactor biosynthesis; molybdopterin biosynthesis. |
| Subunit: | |
Homodimer. Interacts with MobA, MogA and MobB in vivo. {ECO:0000269|PubMed:11428898, ECO:0000269|PubMed:11525167, ECO:0000269|PubMed:12372836}. |
| Similarity: | |
Belongs to the MoeA family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.