|
|
||
|
|
|
|
|
UniProt functional annotation for P53178 | ||
|
|
|
|
|
|
||
| UniProt code: P53178. |
|
||
| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
|
||
|
||
| Function: | |
Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. {ECO:0000269|PubMed:15615718, ECO:0000269|PubMed:16100110}. |
|
||
| Catalytic activity: | |
Reaction=N-acetyl-alpha-D-glucosaminyl-diphosphodolichol + UDP-N- acetyl-alpha-D-glucosamine = H(+) + N,N'-diacetylchitobiosyl diphosphodolichol + UDP; Xref=Rhea:RHEA:23380, Rhea:RHEA-COMP:9519, Rhea:RHEA-COMP:9520, ChEBI:CHEBI:15378, ChEBI:CHEBI:57269, ChEBI:CHEBI:57705, ChEBI:CHEBI:58223, ChEBI:CHEBI:58427; EC=2.4.1.141; |
| Subunit: | |
Heterodimer with ALG14 to form a functional enzyme. |
| Subcellular location: | |
Endoplasmic reticulum {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16100110}. |
| Miscellaneous: | |
Present with 1950 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the glycosyltransferase 28 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.