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UniProt functional annotation for B2KPN7 | ||
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| UniProt code: B2KPN7. |
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| Organism: | |
Conus marmoreus (Marble cone). |
| Taxonomy: | |
Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Conus. |
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| Function: | |
May act as a neurotoxin. |
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| Subcellular location: | |
Secreted {ECO:0000269|PubMed:18355315}. |
| Tissue specificity: | |
Expressed by the venom duct. {ECO:0000305|PubMed:18355315}. |
| Ptm: | |
The D-phenylalanine is essential to the structural conformation. {ECO:0000269|PubMed:18355315}. |
| Ptm: | |
Since conomarphin is a cysteine-free peptide, hydroxyproline plays a critical role in maintaining a restricted conformation of the peptide. |
| Miscellaneous: | |
The mature peptide does not contain cysteine residues. {ECO:0000305}. |
| Miscellaneous: | |
The amino acid sequence of conomarphin is identical to that of C.imperialis Im-conomarphin (AC P0CH39). Their nucleotide sequences are not identical. {ECO:0000305}. |
| Similarity: | |
Belongs to the conotoxin M superfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.