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UniProt functional annotation for Q9UXC4 | ||
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| UniProt code: Q9UXC4. |
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| Organism: | |
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus). |
| Taxonomy: | |
Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus. |
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| Function: | |
Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. {ECO:0000255|HAMAP-Rule:MF_00623, ECO:0000269|PubMed:17078816, ECO:0000269|PubMed:19053279, ECO:0000269|PubMed:20488184}. |
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| Subunit: | |
Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with a hexameric ring- like arrangement composed of 3 Rrp41-Rrp42 heterodimers. {ECO:0000255|HAMAP-Rule:MF_00623, ECO:0000269|PubMed:17380186, ECO:0000269|PubMed:20090900, ECO:0000269|PubMed:22503705, ECO:0000269|PubMed:23319881}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00623}. |
| Domain: | |
Contains an N-terminal domain that mediates interactions with the hexameric ring, a central S1 domain and a C-terminal KH domain. The KH domain is required for efficient RNA degradation, but is not responsible for poly(A) preference. {ECO:0000269|PubMed:17380186, ECO:0000269|PubMed:22503705}. |
| Similarity: | |
Belongs to the RRP4 family. {ECO:0000255|HAMAP- Rule:MF_00623}. |
Annotations taken from UniProtKB at the EBI.