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UniProt functional annotation for Q5SIW3 | ||
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| UniProt code: Q5SIW3. |
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| Organism: | |
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8). |
| Taxonomy: | |
Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus. |
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| Function: | |
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. {ECO:0000255|HAMAP-Rule:MF_01382}. |
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| Catalytic activity: | |
Reaction=ATP + H(2)O + cellular protein(Side 1) = ADP + phosphate + cellular protein(Side 2).; EC=7.4.2.8; Evidence={ECO:0000255|HAMAP- Rule:MF_01382}; |
| Subunit: | |
Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved. Monomer and homodimer. {ECO:0000269|PubMed:17059823}. |
| Subcellular location: | |
Cell inner membrane {ECO:0000255|HAMAP- Rule:MF_01382}; Peripheral membrane protein {ECO:0000255|HAMAP- Rule:MF_01382}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_01382}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01382}. Note=Distribution is 50- 50. {ECO:0000255|HAMAP-Rule:MF_01382}. |
| Similarity: | |
Belongs to the SecA family. {ECO:0000255|HAMAP- Rule:MF_01382}. |
Annotations taken from UniProtKB at the EBI.