UniProt functional annotation for Q5SHE1

UniProt code: Q5SHE1.

Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
Taxonomy: Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
 
Function: Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP). {ECO:0000256|HAMAP-Rule:MF_01224}.
 
Catalytic activity: Reaction=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate; Xref=Rhea:RHEA:49580, ChEBI:CHEBI:33019, ChEBI:CHEBI:59648, ChEBI:CHEBI:131766; EC=4.6.1.17; Evidence={ECO:0000256|ARBA:ARBA00001637, ECO:0000256|HAMAP-Rule:MF_01224};
Pathway: Cofactor biosynthesis; molybdopterin biosynthesis. {ECO:0000256|ARBA:ARBA00005046, ECO:0000256|HAMAP-Rule:MF_01224}.
Subunit: Homohexamer; trimer of dimers. {ECO:0000256|HAMAP- Rule:MF_01224}.
Similarity: Belongs to the MoaC family. {ECO:0000256|HAMAP- Rule:MF_01224}.

Annotations taken from UniProtKB at the EBI.