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PDBsum entry 2hex
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Blood clotting
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PDB id
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2hex
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Contents |
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* Residue conservation analysis
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References listed in PDB file
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Key reference
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Title
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Decamers observed in the crystals of bovine pancreatic trypsin inhibitor.
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Authors
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J.Lubkowski,
A.Wlodawer.
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Ref.
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Acta Crystallogr D Biol Crystallogr, 1999,
55,
335-337.
[DOI no: ]
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PubMed id
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Abstract
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The structure of bovine pancreatic trypsin inhibitor (BPTI) has been solved at
2.1 A resolution in a new crystal form (space group P6422 with unit-cell
dimensions a = b = 95.0, c = 158.1 A). The asymmetric unit is a pentamer, but a
decamer is created by application of crystallographic symmetry. The decamer of
BPTI is only the fourth such assembly reported to date in the Protein Data Bank.
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Figure 1.
Figure 1 Stereoscopic drawing of the C  traces
for four representative previously determined pentamers and two
decamers, compared with the currently obtained structure of
BPTI. (a) Cholera toxin, (b) C-reactive protein, (c) mouse
polyomavirus VP1 coat protein, (d) cartilage oligomeric matrix
protein, (e) GTP cyclohydrolase I, (f) muconolactone isomerase,
(g) cyclophilin A, (h) BPTI (this work).
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The above figure is
reprinted
by permission from the IUCr:
Acta Crystallogr D Biol Crystallogr
(1999,
55,
335-337)
copyright 1999.
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