UniProt functional annotation for P63488

UniProt code: P63488.

Organism: Staphylococcus aureus (strain Mu50 / ATCC 700699).
Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus.
 
Function: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). {ECO:0000255|HAMAP-Rule:MF_00120}.
 
Catalytic activity: Reaction=ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate; Xref=Rhea:RHEA:17521, Rhea:RHEA-COMP:9681, Rhea:RHEA-COMP:9684, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58359, ChEBI:CHEBI:78520, ChEBI:CHEBI:78521, ChEBI:CHEBI:456216; EC=6.3.5.7; Evidence={ECO:0000255|HAMAP-Rule:MF_00120};
Subunit: Heterotrimer of A, B and C subunits. {ECO:0000255|HAMAP- Rule:MF_00120}.
Similarity: Belongs to the amidase family. GatA subfamily. {ECO:0000255|HAMAP-Rule:MF_00120}.

Annotations taken from UniProtKB at the EBI.