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UniProt functional annotation for P11065 | ||
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| UniProt code: P11065. |
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| Organism: | |
Bacillus subtilis (strain 168). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus. |
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| Function: | |
Negative regulator of protease production and sporulation. Acts by binding directly to the promoter of protease genes (aprE and nprE), and by repressing oligopeptide permease operons (appABCDF and oppABCDF), thereby preventing uptake of oligopeptides required for initiation of sporulation. Acts with SinR as a corepressor of epr expression. {ECO:0000255|HAMAP-Rule:MF_01911, ECO:0000269|PubMed:10383984, ECO:0000269|PubMed:16923912, ECO:0000269|PubMed:1906467}. |
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| Subunit: | |
Homodimer. Interacts with SinR. {ECO:0000255|HAMAP- Rule:MF_01911, ECO:0000269|PubMed:15104138, ECO:0000269|PubMed:16923912, ECO:0000269|Ref.10}. |
| Induction: | |
Negatively regulated by the Mrp homolog protein SalA and by SenS. |
Annotations taken from UniProtKB at the EBI.