UniProt functional annotation for P47224

UniProt code: P47224.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1, RAB3A and RAB10, but is less active on these proteins than on the SEC4 protein (PubMed:31540829). Might play a general role in vesicular transport. {ECO:0000269|PubMed:31540829}.
 
Subunit: Interacts with RAB8A. {ECO:0000269|PubMed:16541104}.
Tissue specificity: Ubiquitous.
Similarity: Belongs to the DSS4/MSS4 family. {ECO:0000255|PROSITE- ProRule:PRU01132}.

Annotations taken from UniProtKB at the EBI.