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UniProt functional annotation for P68175 | ||
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| UniProt code: P68175. |
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| Organism: | |
Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Rauvolfiinae; Rauvolfia. |
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| Function: | |
Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. |
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| Catalytic activity: | |
Reaction=3alpha(S)-strictosidine + H2O = secologanin + tryptamine; Xref=Rhea:RHEA:15013, ChEBI:CHEBI:15377, ChEBI:CHEBI:18002, ChEBI:CHEBI:57887, ChEBI:CHEBI:58193; EC=4.3.3.2; |
| Pathway: | |
Alkaloid biosynthesis; 3alpha(S)-strictosidine biosynthesis; 3alpha(S)-strictosidine from secologanin and tryptamine: step 1/1. |
| Subunit: | |
Monomer. |
| Subcellular location: | |
Vacuole. |
| Tissue specificity: | |
Expressed predominantly, but not exclusively, in the root. {ECO:0000269|PubMed:1567228}. |
| Similarity: | |
Belongs to the strictosidine synthase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.