|
|
||
|
|
|
|
|
UniProt functional annotation for Q98157 | ||
|
|
|
|
|
|
||
| UniProt code: Q98157. |
|
||
| Organism: | |
Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus). |
| Taxonomy: | |
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus. |
|
||
|
||
| Function: | |
Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. |
|
||
| Subunit: | |
Monomer. Interacts with human chomokine receptor CXCR4 (PubMed:25612609). {ECO:0000269|PubMed:25612609}. |
| Subcellular location: | |
Secreted. |
| Similarity: | |
Belongs to the intercrine beta (chemokine CC) family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.